African Evaluation Database

9120 records found

Source	Electronic ID	Title	Authors	Publication Year	Source Title	Volume	Issue	DOI	Affiliations	Authors with Affiliations	Abstract	Author Keywords	Index Keywords▲	Funding Details
Scopus	2-s2.0-84909983185	Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters	Smit F.J., Van Biljon R.A., Birkholtz L.-M., N'da D.D.	2014	European Journal of Medicinal Chemistry	90	None	10.1016/j.ejmech.2014.11.016	Center of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Afr...	Smit, F.J., Center of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroo...	A series of dihydroartemisinyl-chalcone esters were synthesized through esterification of chalcon...	Antitumor; Chalcone; Dihydroartemisinin; Malaria; Plasmodium falciparum	10 aplha dihydroartemisinyl 4 [(1e) 3 (5 methylfuran 2 yl) 3 oxoprop 1 en 1 yl]benzoate; 10 beta ...	NRF, UID 76443, National Research Foundation	View
Scopus	2-s2.0-84874159362	Azide-alkyne cycloaddition en route to 1H-1,2,3-triazole-tethered 7-chloroquinoline-isatin chimer...	Raj R., Singh P., Singh P., Gut J., Rosenthal P.J., Kumar V.	2013	European Journal of Medicinal Chemistry	62	None	10.1016/j.ejmech.2013.01.032	Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, India; Department of Chemist...	Raj, R., Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, India; Singh, P., D...	We describe the synthesis and antimalarial activities of 1H-1,2,3-triazole tethered 7-chloroquino...	1H-1,2,3-triazole; 7-Chloroquinoline-isatin conjugates; Antimalarial evaluation; Structure-activi...	1 [1 (7 chloro quinolin 4 yl) 1h [1,2,3]triazol 4 ylmethyl] 1h indole 2,3 dione; 1 [1 (7 chloro q...	None	View
Scopus	2-s2.0-66849127677	Evaluation of cryptolepine and huperzine derivatives as lead compounds towards new agents for the...	Oluwafemi A.J., Okanla E.O., Camps P., Muñoz-Torrero D., Mackey Z.B., Chiang P.K., Seville S., Wr...	2009	Natural Product Communications	4	2	None	Department of Zoology, University of Ilorin, Ilorin, Nigeria; Laboratori de Química Farmacèutica ...	Oluwafemi, A.J., Department of Zoology, University of Ilorin, Ilorin, Nigeria; Okanla, E.O., Depa...	The alkaloid cryptolepine (1) and eight synthetic analogues (2-8) were assessed for in vitro acti...	Cryptolepine; Cryptolepis sanguinolenta; Huperzia serrata; Huperzine; Huprine; Trypanosomiasis	11 chlorocryptolepine; 2 chlorocryptolepine; 2 fluorocryptolepine; 2,7 dibromocryptolepine; 7 bro...	None	View
Scopus	2-s2.0-84862338892	Evaluation of the acetone and aqueous extracts of mature stem bark of Sclerocarya birrea for anti...	Tanih N.F., Ndip R.N.	2012	Evidence-based Complementary and Alternative Medicine	2012	None	10.1155/2012/834156	Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Fo...	Tanih, N.F., Department of Biochemistry and Microbiology, Faculty of Science and Agriculture, Uni...	We assayed the antimicrobial activity of acetone and aqueous extracts of the stem bark of Scleroc...	None	1,1 diphenyl 2 picrylhydrazyl; 2,2' azinobis(3 ethylbenzothiazoline 6 sulfonic acid); acetone; am...	None	View
Scopus	2-s2.0-34247483435	Evaluation of antioxidant activity and the fatty acid profile of the leaves of Vernonia amygdalin...	Erasto P., Grierson D.S., Afolayan A.J.	2007	Food Chemistry	104	2	10.1016/j.foodchem.2006.12.013	Department of Botany, University of Fort Hare, P/Bag X1314, Alice, 5700, South Africa	Erasto, P., Department of Botany, University of Fort Hare, P/Bag X1314, Alice, 5700, South Africa...	The leaves of Vernonia amygdalina were examined for antioxidant activity and analysed for their f...	Antioxidant activity; Fatty acids; Free radical scavenging; Vernonia amygdalina	1,1 diphenyl 2 picrylhydrazyl; 2,2' azinobis(3 ethylbenzothiazoline 6 sulfonic acid); acetone; an...	None	View
Scopus	2-s2.0-84863803528	Evaluation of polyphenolic content and antioxidant activity of Artemisia afra jacq. ex willd. aqu...	Sunmonu T.O., Afolayan A.J.	2012	Pakistan Journal of Nutrition	11	7	None	Department of Biochemistry, College of Natural Sciences, Federal University of Agriculture, Abeok...	Sunmonu, T.O., Department of Biochemistry, College of Natural Sciences, Federal University of Agr...	Artemisia afra Jacq. ex Willd. is widely used in South African traditional medicine for the treat...	ABTS; Antioxidant; Artemisia afra; DPPH; Free radicals; Total phenolics	1,1 diphenyl 2 picrylhydrazyl; 2,2' azinobis(3 ethylbenzothiazoline 6 sulfonic acid); antioxidant...	None	View
Scopus	2-s2.0-84928650100	Development and evaluation of liquid oral phytoformulation of Phyllanthus amarus	Avbunudiogba J.A., Alalor C.A., Builders P.F., Odozie S.	2013	Journal of Pharmacy Research	6	9	10.1016/j.jopr.2013.08.029	Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Delta State University,...	Avbunudiogba, J.A., Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Del...	Background: The leaves of Phyllanthus amarus (family: Euphorbiaceae) is reported to have good med...	Antitussive property; Aqueous extract; Herbal syrup; Phyllanthus amarus; Phytochemical properties	1,1 diphenyl 2 picrylhydrazyl; alcohol; citric acid; glycerol; Phyllanthus amarus extract; water;...	None	View
Scopus	2-s2.0-79251520952	Evaluation of in-vitro antioxidant activities of methanol extracts of Persea americana and Cnidos...	Asaolu M.F., Asaolu S.S., Fakunle J.B., Emman-Okon B.O., Ajayi E.O., Togun R.A.	2010	Pakistan Journal of Nutrition	9	11	10.3923/pjn.2010.1074.1077	Department of Biochemistry, University of Ado-Ekiti, P.M.B. 5363, Ado- Ekiti, Nigeria; Department...	Asaolu, M.F., Department of Biochemistry, University of Ado-Ekiti, P.M.B. 5363, Ado- Ekiti, Niger...	The present study was undertaken to investigate the antioxidant activities of Persea americana an...	Antioxidant activities; Methanol extracts; Phytochemical screening; Radical-scavenging activity	1,1 diphenyl 2 picrylhydrazyl; alkaloid; anthraquinone derivative; antioxidant; ascorbic acid; ca...	None	View
Scopus	2-s2.0-79957877665	Evaluation of the antimalarial potential of Vernonia ambigua kotschy and peyr (Asteraceae)	Builders M.I., Wannang N.N., Ajoku G.A., Builders P.F., Onsadipe A., Aguiyi J.C.	2011	International Journal of Pharmacology	7	2	10.3923/ijp.2011.238.247	Department of Pharmacology, College of Medical Sciences, Bingham University, Jos, Nigeria; Depart...	Builders, M.I., Department of Pharmacology, College of Medical Sciences, Bingham University, Jos,...	Some traditional medicine practitioners in Nigeria have claimed the use of the decoction of the w...	Antioxidant property; Antiplasmodial activity; Oral median lethal dose; Phytochemical components;...	1,1 diphenyl 2 picrylhydrazyl; alkaloid; anthraquinone derivative; ascorbic acid; chloroquine; es...	None	View
Scopus	2-s2.0-84884254772	Evaluation of the anti-diabetic and antioxidant activities of the methanol leaf extract of Berlin...	Ode O.J., Nwaehujor C.O., Nwinyi C.F.	2013	Journal of Medical Sciences (Faisalabad)	13	8	10.3923/jms.2013.743.748	Department of Veterinary Pharmacology and Toxicology, University of Abuja, Nigeria; Department of...	Ode, O.J., Department of Veterinary Pharmacology and Toxicology, University of Abuja, Nigeria; Nw...	Hypoglycemic and anti-oxidant activities of the methanol leaf extract of Berlinia grandiflora wer...	Anti-diabetic; Anti-oxidant; Berlinia glandiflora; DPPH; FRAP; Glibenclamide; Osmotic fragility; ...	1,1 diphenyl 2 picrylhydrazyl; alkaloid derivative; antidiabetic agent; antioxidant; ascorbic aci...	None	View
Scopus	2-s2.0-70349515848	Evaluation of antioxidant properties of phaulopsis fascisepala C.B.Cl. (Acanthaceae)	Adesegun S.A., Fajana A., Orabueze C.I., Coker H.A.B.	2009	Evidence-based Complementary and Alternative Medicine	6	2	10.1093/ecam/nem098	Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, PMB 12003, Lagos, Nigeria;...	Adesegun, S.A., Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, PMB 12003,...	The antioxidant activities of crude extract of Phaulopsis fascisepala leaf were evaluated and com...	Iron chelating power; Phenolic content; Radical scavenging; Reducing power	1,1 diphenyl 2 picrylhydrazyl; alpha tocopherol; antioxidant; ascorbic acid; butylcresol; ferric ...	None	View
Scopus	2-s2.0-84928650473	Evaluation of the invitro anti-oxidant activity of Alternanthera brasiliana leaves	Enechi O.C., Odo C.E., Wuave C.P.	2013	Journal of Pharmacy Research	6	9	10.1016/j.jopr.2013.09.006	Pharmacology Research Unit, Department of Biochemistry, University of Nigeria, Nsukka, Nigeria	Enechi, O.C., Pharmacology Research Unit, Department of Biochemistry, University of Nigeria, Nsuk...	Background and aim: Alternanthera brasiliana belongs to the family, Amaranthaceae and is popularl...	Alternanthera brasiliana; Anti-oxidants; Ethanol; Free radical and lipid peroxidation	1,1 diphenyl 2 picrylhydrazyl; Alternanthera brasiliana extract; antioxidant; ascorbic acid; carb...	None	View
Scopus	2-s2.0-84940025563	In vitro evaluation of the comprehensive antimicrobial and antioxidant properties of curtisia den...	Fadipe V.O., Mongalo N.I., Opoku A.R.	2015	EXCLI Journal	14	None	10.17179/excli2015-351	Department of Chemistry, University of Zululand, Private Bag X1001, KwaDlangezwa, South Africa; C...	Fadipe, V.O., Department of Chemistry, University of Zululand, Private Bag X1001, KwaDlangezwa, S...	Curtisia dentata is used in African traditional medicine to treat variety of infections. C. denta...	Antimicrobial; Antioxidant; Curtisia dentata; Cytotoxicity; Ethnomedicine; β-sitosterol	1,1 diphenyl 2 picrylhydrazyl; antiinfective agent; antioxidant; ascorbic acid; betulic acid; Cur...	None	View
Scopus	2-s2.0-73449124055	Evaluation of antioxidant activity of leave extract of Bauhinia rufescens Lam. (Caesalpiniaceae)	Aliyu A.B., Ibrahim M.A., Musa A.M., Ibrahim H., Abdulkadir I.E., Oyewale A.O.	2009	Journal of Medicinal Plants Research	3	8	None	Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria; Department of Biochemistry, Ahm...	Aliyu, A.B., Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria; Ibrahim, M.A., Dep...	Antioxidant evaluation of Bauhinia rufescens used in Northern Nigerian traditional medicine, was ...	Antioxidants; Bauhinia rufescens; DPPH; Free radicals; Reducing power; Total phenolics	1,1 diphenyl 2 picrylhydrazyl; ascorbic acid; Bauhinia rufescens extract; flavanoid; free radical...	None	View
Scopus	2-s2.0-78650361088	Evaluation of Antioxidant Potential of Melanthera scandens	Adesegun S.A., Alabi S.O., Olabanji P.T., Coker H.A.B.	2010	JAMS Journal of Acupuncture and Meridian Studies	3	4	10.1016/S2005-2901(10)60047-7	Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, Lagos, Nigeria; Department...	Adesegun, S.A., Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, Lagos, Nig...	A methanol extract of dried leaves of Melanthera scandens was examined for antioxidant activities...	Antioxidant activities; Lipid peroxidation; Melanthera scandens; Radical scavengindg; Reducing power	1,1 diphenyl 2 picrylhydrazyl; ascorbic acid; edetic acid; gallic acid; herbaceous agent; linolei...	None	View
Scopus	2-s2.0-18844452979	Radiosynthesis and evaluation of two novel 123I-labeled 2-methyl-4-nitroimidazole derivatives as ...	Rossouw D.D., Lötter M.G., Du Raan H., Jansen S.E., Höhn A., Burger B.V.	2005	Nuclear Medicine and Biology	32	4	10.1016/j.nucmedbio.2005.02.001	iThemba Lab. for Accel.-Based Sci., PO Box 722, Somerset-West 7129, South Africa; Department of M...	Rossouw, D.D., iThemba Lab. for Accel.-Based Sci., PO Box 722, Somerset-West 7129, South Africa; ...	Introduction: The inflammation- and infection-seeking properties of 131I-labeled ornidazole, a 5-...	2-Methyl-4-nitroimidazoles; 123I; Imaging; Infection; Radiosynthesis	1 [(1 hydroxy 3 iodoprop 2 yloxy)methyl] 2 methyl 4 nitroimidazole i 123; 1 [(1 iodoprop 2 yloxy)...	None	View
Scopus	2-s2.0-84858738941	Validation of noninvasive monitoring of adrenocortical endocrine activity in ground-feeding aardw...	Ganswindt A., Muilwijk C., Engelkes M., Muenscher S., Bertschinger H., Paris M., Palme R., Camero...	2012	Physiological and Biochemical Zoology	85	2	10.1086/664591	Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, Pretoria...	Ganswindt, A., Mammal Research Institute, Department of Zoology and Entomology, University of Pre...	Biologically inert material in feces may confound interpretations of noninvasive fecal endocrine ...	None	11 oxoetiocholanolone; 11-ketoetiocholanolone; corticotropin; drug derivative; etiocholanolone; g...	None	View
Scopus	2-s2.0-84866121518	Cobalt mediated ring contraction reaction of lapachol and initial antibacterial evaluation of nap...	Eyong K.O., Kumar S.P., Kuete V., Folefoc G.N., Langmi H., Meyer M.J.J., Lall N., Baskaran S.	2012	Medicinal Chemistry Research	21	8	10.1007/s00044-011-9788-9	Department of Chemistry, Indian Institute of Technology, Madras, Chennai 600 036, India; Departme...	Eyong, K.O., Department of Chemistry, Indian Institute of Technology, Madras, Chennai 600 036, In...	The synthesis of 2-hydroxy-2-(3-methylbut- 2-enyl)-2H-indene-1,3-dione 3, from lapachol which inv...	Antibacterial; Antituberculosis; Lapachol; Naphthoquinones; Ring contraction	1 (2,3,4,9 tetrahydro 4,9 dioxonaphtho[2,3 b]furany 2 yl) 1 methylethyl nitrate; 1,4 dihydro 3 hy...	None	View
Scopus	2-s2.0-49649112709	Synthesis and biological evaluation of novel 4-substituted 1-{[4-(10,15,20-triphenylporphyrin-5-y...	Bhat A.R., Athar F., Van Zyl R.L., Chen C.-T., Azam A.	2008	Chemistry and Biodiversity	5	5	10.1002/cbdv.200890073	Department of Chemistry, Jamia Millia Islamia, Jamia Nagar, New Delhi-110025, India; Center for I...	Bhat, A.R., Department of Chemistry, Jamia Millia Islamia, Jamia Nagar, New Delhi-110025, India; ...	A novel series of 4-substituted 1-{[4-(10,15,20-triphenylporphyrin-5-yl) phenyl]methylidene}thios...	None	1,2,3,4 tetrahydro n' [[4 (10,15,20 triphenylporphyrin 5 yl)phenyl]methylidene]quinoline 1 carbot...	None	View
Scopus	2-s2.0-84869748833	Imidazopyridine-based inhibitors of glycogen synthase kinase 3: Synthesis and evaluation of amide...	Yngve U., Söderman P., Svensson M., Rosqvist S., Arvidsson P.I.	2012	Chemistry and Biodiversity	9	11	10.1002/cbdv.201200308	Medicinal Chemistry IScience, CNSP IMed, AstraZeneca RandD Södertälje, SE-151 85 Södertälje, Swed...	Yngve, U., Medicinal Chemistry IScience, CNSP IMed, AstraZeneca RandD Södertälje, SE-151 85 Söder...	In this study, we explored the effect of bioisostere replacement in a series of glycogen synthase...	1,2,4-Oxadiazoles; Bioisosteres; Glycogen Synthase Kinase 3 (GSK3); Imidazopyridine; Inhibitors; ...	1,2,4 oxadiazole derivative; 2 [4 (morpholin 4 ylmethyl)phenyl] 7 [2 (piperidin 1 yl) 1,3 thiazol...	None	View

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