African Evaluation Database

9120 records found

Source	Electronic ID	Title	Authors	Publication Year	Source Title	Volume	Issue	DOI	Affiliations	Authors with Affiliations	Abstract	Author Keywords	Index Keywords	Funding Details
Scopus	2-s2.0-34247216261	Evaluation of anti-diarrhoeal and anti-ulcerogenic potential of ethanol extract of Carpolobia lut...	Nwafor P.A., Bassey A.I.L.	2007	Journal of Ethnopharmacology	111	3	10.1016/j.jep.2007.01.019	Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, PMB 1017, Uyo,...	Nwafor, P.A., Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, ...	The effect of ethanol extract of Carpolobia lutea leaves on experimentally induced diarrhoea and ...	Anti-diarroheal; Anti-ulcerogenic; Carpolobia lutea leaves; Ethanol extract; Rodents	alcohol; alpha 2 adrenergic receptor; anthraquinone derivative; cardiac glycoside; Carpolobia lut...	None	View
Scopus	2-s2.0-68149156899	Evaluation of in vivo antimalarial activities of ethanolic leaf and seed extracts of telfairia oc...	Okokon J.E., Ekpo A.J., Eseyin O.A.	2009	Journal of Medicinal Food	12	3	10.1089/jmf.2008.0099	Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria; ...	Okokon, J.E., Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, ...	The leaves and seeds of Telfairia occidentalis are used as vegetables in making soups in Southern...	Antimalarial activity; Antiplasmodial activity; Telfairia occidentalis	chloroquine; plant extract; Telfairia occidentalis extract; unclassified drug; animal experiment;...	None	View
Scopus	2-s2.0-34247235241	Evaluation of antiplasmodial activity of ethanolic seed extract of Picralima nitida	Okokon J.E., Antia B.S., Igboasoiyi A.C., Essien E.E., Mbagwu H.O.C.	2007	Journal of Ethnopharmacology	111	3	10.1016/j.jep.2006.12.016	Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria; ...	Okokon, J.E., Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, ...	The in vivo antiplasmodial activity of the ethanol seed extract of Picralima nitida grown particu...	Antiplasmodial; Malaria; Picralima nitida	chloroquine; Picralima nitida extract; plant extract; unclassified drug; animal experiment; anima...	None	View
Scopus	2-s2.0-23844464755	Pharmacological screening and evaluation of antiplasmodial activity of Croton zambesicus against ...	Okokon J.E., Ofodum K.C., Ajibesin K.K., Danladi B., Gamaniel K.S.	2005	Indian Journal of Pharmacology	37	4	None	Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria; ...	Okokon, J.E., Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, ...	Objective: To evaluate the antiplasmodial activity of leaf extract of Croton zambesicus on chloro...	Malaria; Schizontocide	chloroquine; croton zambesicus extract; plant extract; pyrimethamine; unclassified drug; animal c...	None	View
Scopus	2-s2.0-33745747755	Evaluation of in vivo antiplasmodial activity of Aspilia africana	Okokon J.E., Nwidu L.L., Essiet G.A.	2006	International Journal of Pharmacology	2	3	10.3923/ijp.2006.348.351	Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, Uyo, Nigeria; ...	Okokon, J.E., Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Uyo, ...	The antiplasmodial activity of ethanol leaf extract of Aspilia africana was evaluated in mice inf...	Antimalarial; Antiplasmodial; Aspilia africana; Plasmodium berghei; Schizonticidal	antimalarial agent; Aspilia africana extract; chloroquine; plant extract; unclassified drug; acut...	None	View
Scopus	2-s2.0-84905511026	Evaluation of anthelmintic activity of Nigerian ethnoveterinary plants; Cassia occidentalis and G...	Suleiman M.M., Mamman M., Sidiama A., Ighoja E.J., Tauheed M., Talba A.M.	2014	Veterinary World	7	7	10.14202/vetworld.2014.536-541	Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ahmadu Bello Universit...	Suleiman, M.M., Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ahmadu...	Aim: This study was designed to evaluate the anthelmintic activity of the stem-barks of Cassia oc...	Anthelmintic; Cassia occidentalis; Guiera senegalensis; Haemonchus contortus; Medicinal plants	Haemonchus contortus; Senna occidentalis; Vermes	None	View
Scopus	2-s2.0-84909943797	Evaluation of antinociceptive and anti-inflammatory activities of standardised rootbark extract o...	Adzu B., Amizan M.B., Okhale S.E.	2014	Journal of Ethnopharmacology	None	PART A	10.1016/j.jep.2014.10.030	Department of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Dev...	Adzu, B., Department of Pharmacology and Toxicology, National Institute for Pharmaceutical Resear...	Ethnopharmacological relevance Xeromphis nilotica (Stapf) Keay (Rubiaceae), popularly known as 'b...	Anti-inflammatory; Antinociceptive; Aqueous extract; Xeromphis nilotica	acetic acid; acetylsalicylic acid; analgesic agent; antiinflammatory agent; formaldehyde; ovalbum...	None	View
Scopus	2-s2.0-40549140122	Evaluation of anti-diarrhoeal properties of methanolic Root extract of Piliostigma reticulatum in...	Salawu O.A., Tijani A.Y., Obidike I.C., Chindo B.A.	2007	Journal of Phytomedicine and Therapeutics	12	None	None	Department of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Dev...	Salawu, O.A., Department of Pharmacology and Toxicology, National Institute for Pharmaceutical Re...	Piliostigma reticulatum (DC) Hoechst (Leguminosae) is an evergreen shrub reputed to possess a num...	Anti-diarrhoeal activity; Gastrointestinal tract; Piliostigma reticulatum; Rat	alkaloid; antidiarrheal agent; atropine; balsam; castor oil; glycoside; methanol; Piliostigma ret...	None	View
Scopus	2-s2.0-84868148971	Evaluation of antimalarial potential of aqueous stem bark extract of bombax buonopozense P. Beauv...	Iwuanyanwu T.C., Akuodor G.C., Essien A.D., Nwinyi F.C., Akpan J.L., Okorafor D.O., Osunkwo U.A.	2011	Eastern Journal of Medicine	17	2	None	Department of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Dev...	Iwuanyanwu, T.C., Department of Pharmacology and Toxicology, National Institute for Pharmaceutica...	The treatment of malaria in Africa is becoming increasingly difficult due to rising prevalence of...	Antimalaria; Bombax buonopozense; Medicinal plant; Mice; Plasmodium berghei	antimalarial agent; Bombax buonopozense extract; chloroquine; plant extract; unclassified drug; a...	None	View
Scopus	2-s2.0-84908452073	Wound-healing activity of the aqueous leaf extract and fractions of ficus exasperata(Moraceae) an...	Umeh V., Ilodigwe E., Ajaghaku D., Erhirhie E., Moke G., Akah P.	2014	Journal of Traditional and Complementary Medicine	4	4	10.4103/2225-4110.139105	Department of Pharmacology and Toxicology, Nnamdi Azikiwe University Awka, Anambra State, Nigeria...	Umeh, V., Department of Pharmacology and Toxicology, Nnamdi Azikiwe University Awka, Anambra Stat...	Ficus exasperata have been reported to have wide applications in the treatment of many human dise...	Chronic diseases; Ficus exasperata; Hematological parameters; Liver enzymes; Toxicity; Wound healing	None	None	View
Scopus	2-s2.0-84870325433	Evaluation of the anti-asthma activity of aqueous root bark extract of ficus exasperata vahl (Mor...	Okpo S.O., Eze G.I., Ajaanonwu I.H., Ijei O.L., Uwaya D.O., Ologe V.	2012	International Journal of Health Research	5	1	None	Department of Pharmacology and Toxicology, University of Benin, Benin City 300001, Nigeria; Depar...	Okpo, S.O., Department of Pharmacology and Toxicology, University of Benin, Benin City 300001, Ni...	Purpose: Ficus exasperata Vahl is used in folk medicine in the management of various ailments inc...	Anaphylaxis; F. exasperata; Histamine aerosol; Ovalbumin; Trachea	antiasthmatic agent; cromoglycate disodium; Ficus exasperata extract; histamine H1 receptor; plan...	None	View
Scopus	2-s2.0-84948425940	Neurobehavioural evaluation of Lophira alata (Ochnaceae) stem bark extract in mice	Iniaghe L.O., Ighodaro I., Magaji M.G., Tabot T.P., Maduka I.T.	2015	Journal of Basic and Clinical Physiology and Pharmacology	26	6	10.1515/jbcpp-2014-0096	Department of Pharmacology and Toxicology, University of Benin, Benin City, Nigeria; Department o...	Iniaghe, L.O., Department of Pharmacology and Toxicology, University of Benin, Benin City, Nigeri...	Stem bark and leaves of Lophira alata (Family: Ochnaceae) have been used traditionally for their ...	Anxiolysis; convulsion; depression; ethnomedicine; L ophira alata	alkaloid derivative; diazepam; flavonoid; imipramine; Lophira alata extract; pentetrazole; phenob...	None	View
Scopus	2-s2.0-73749085582	Evaluation of the diuretic and analgesic activities of the rhizomes of Rumex abyssinicus Jacq in ...	Mekonnen T., Urga K., Engidawork E.	2010	Journal of Ethnopharmacology	127	2	10.1016/j.jep.2009.10.020	Department of Pharmacology, School of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia; De...	Mekonnen, T., Department of Pharmacology, School of Pharmacy, Addis Ababa University, Addis Ababa...	Aim of the study: Rumex abyssinicus Jacq (Polygonaceae) has been used traditionally for treatment...	Acetic acid-writhing test; Analgesic activity; Diuretic effect; Hot-plate test; Rumex abyssinicus	acetylsalicylic acid; analgesic agent; diuretic agent; furosemide; morphine; plant extract; Rumex...	None	View
Scopus	2-s2.0-45749147106	Toxicological evaluation of the anti-malarial herb Cryptolepis sanguinolenta in rodents	Ansah C., Mfoafo E.A., Woode E., Opoku-Okrah C., Owiredu W.K.B.A., Duwiejua M.	2008	Journal of Pharmacology and Toxicology	3	5	10.3923/jpt.2008.335.343	Department of Pharmacology, College of Health Sciences, Kwame Nkrumah University of Science and T...	Ansah, C., Department of Pharmacology, College of Health Sciences, Kwame Nkrumah University of Sc...	In this study, we evaluated the aqueous extract of the roots of Cryptolepis sanguinolenta (Peripl...	Antimalarial; CNS depressant; Cryptolepis sanguinolenta; Haematological parameters; Rodents; Slee...	alanine aminotransferase; albumin; alkaline phosphatase; aminotransferase; antimalarial agent; as...	None	View
Scopus	2-s2.0-77953426613	Evaluation of analgesic and anti-inflammatory compounds from Stereospermum kunthianum (Bignoniaceae)	Ching F.P., Falodun A., Omogbai E.K.I., Okpo S.O., Ozolua R.I., Choudhary M.I.	2009	International Journal of PharmTech Research	1	4	None	Department of Pharmacology, College of Health Sciences, Niger Delta University, Wilberforce Islan...	Ching, F.P., Department of Pharmacology, College of Health Sciences, Niger Delta University, Wilb...	Stereospermum kunthianum (Bignoniaceae) is a woody shrub of the Sudano-Guinea savannah regions of...	Analgesic; Anti-inflammatory activities; Compounds; Stereospermin; Stereospermiside; Stereospermu...	carrageenan; formaldehyde; indometacin; morphine; plant glycoside; sodium chloride; stereospermin...	None	View
Scopus	2-s2.0-77954550586	Safety evaluations of aqueous stem bark extract of Lophira lanceolata in sprague dawley rats	Etuk E., Muhammad A.A.	2010	International Journal of Research in Pharmaceutical Sciences	1	1	None	Department of Pharmacology, College of Health Sciences, Usm anu Danfodiyo University, Sokoto, Nig...	Etuk, E., Department of Pharmacology, College of Health Sciences, Usm anu Danfodiyo University, S...	Lophira lanceolata extract is widely used to enhance sexual performance among the male population...	Lophira lanceolata; Parameters; Sexual stimulant; Toxicity	aminotransferase; hemoglobin; Lophira lanceolata extract; plant extract; unclassified drug; amino...	None	View
Scopus	2-s2.0-77954463694	The pharmacological impact of restricted or non variant diet	Bello S.O.	2010	International Journal of Drug Development and Research	2	1	None	Department of Pharmacology, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria	Bello, S.O., Department of Pharmacology, College of Health Sciences, Usmanu Danfodiyo University,...	Food is often consumed for its nutritive value but food items also contain chemicals that have ph...	None	clomifene; daidzein; genistin; glycyrrhizic acid; phytate; phytoestrogen; soybean protein; zinc; ...	None	View
Scopus	2-s2.0-79957877665	Evaluation of the antimalarial potential of Vernonia ambigua kotschy and peyr (Asteraceae)	Builders M.I., Wannang N.N., Ajoku G.A., Builders P.F., Onsadipe A., Aguiyi J.C.	2011	International Journal of Pharmacology	7	2	10.3923/ijp.2011.238.247	Department of Pharmacology, College of Medical Sciences, Bingham University, Jos, Nigeria; Depart...	Builders, M.I., Department of Pharmacology, College of Medical Sciences, Bingham University, Jos,...	Some traditional medicine practitioners in Nigeria have claimed the use of the decoction of the w...	Antioxidant property; Antiplasmodial activity; Oral median lethal dose; Phytochemical components;...	1,1 diphenyl 2 picrylhydrazyl; alkaloid; anthraquinone derivative; ascorbic acid; chloroquine; es...	None	View
Scopus	2-s2.0-84945972384	Evaluation and comparison of the indices of systemic oxidative stress among black-Africans with a...	Awodele O., Oreagba I.A., Olayemi S.O., Oladipo I., Iruegbukpe C.O., Balogun B.G., Balogun M.M., ...	2015	Middle East African Journal of Ophthalmology	22	4	10.4103/0974-9233.167811	Department of Pharmacology, College of Medicine, University of Lagos, Ikeja, Lagos, Nigeria; Depa...	Awodele, O., Department of Pharmacology, College of Medicine, University of Lagos, Ikeja, Lagos, ...	Purpose: Oxidative stress has been implicated in the pathophysiology of glaucoma, cataract, and m...	Anti-oxidants; Cataract; Glaucoma; Oxidative Stress	ascorbic acid; catalase; glutathione; glutathione transferase; lipid; superoxide dismutase; adult...	None	View
Scopus	2-s2.0-84878781412	Preliminary antimicrobial evaluation of DAS-77® - A polyherbal medicine	Awodele O., Akindele A.J., Aniete J., Adeyemi O.O.	2013	Journal of Herbal Medicine	3	2	10.1016/j.hermed.2013.01.002	Department of Pharmacology, College of Medicine, University of Lagos, Lagos, Nigeria	Awodele, O., Department of Pharmacology, College of Medicine, University of Lagos, Lagos, Nigeria...	Ethnobotanical records suggest that plants are the sleeping giants of the pharmaceutical industry...	Antimicrobial activity; DAS-77®; Diarrhoea; Dysentery; Phytomedicine	antibiotic agent; ciprofloxacin; das 77; tetracycline; unclassified drug; antimicrobial activity;...	None	View

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