African Evaluation Database

9120 records found

Source	Electronic ID	Title	Authors	Publication Year	Source Title	Volume	Issue	DOI	Affiliations	Authors with Affiliations	Abstract	Author Keywords	Index Keywords	Funding Details
Scopus	2-s2.0-84908334995	Evaluation of trimetallic Ru(II)- and Os(II)-Arene complexes as potential anticancer agents	Makhubela B.C.E., Meyer M., Smith G.S.	2014	Journal of Organometallic Chemistry	None	None	10.1016/j.jorganchem.2014.08.034	Department of Chemistry, University of Cape Town, Rondebosch, Cape Town, South Africa; Department...	Makhubela, B.C.E., Department of Chemistry, University of Cape Town, Rondebosch, Cape Town, South...	Schiff-base ligands, tris-2-(salicylaldimine ethyl)amine and tris-2-(2-pyridylimine ethyl)amine (...	Cancer; Cytotoxicity; I; Ruthenium(II)-arenes and osmium(II)-arenes; Topoisomerase; Trimetallic	Iodine; Arene complexes; Cancer; Potential anticancer agents; Topoisomerases; Trimetallic; Cytoto...	None	View
Scopus	2-s2.0-84868249509	Synthesis, characterisation and in vitro evaluation of platinum(II) and gold(I) iminophosphine co...	Chiririwa H., Moss J.R., Hendricks D., Smith G.S., Meijboom R.	2013	Polyhedron	49	1	10.1016/j.poly.2012.09.053	Department of Chemistry, University of Cape Town, Private Bag, Rondebosch 7701, South Africa; Div...	Chiririwa, H., Department of Chemistry, University of Cape Town, Private Bag, Rondebosch 7701, So...	The reactions of iminophosphine ligands with [PtCl2(COD)], [PtCl2(DMSO)2], and [Au(tht)Cl] has be...	Anticancer; Gold(I) complexes; Iminophosphines; Platinum(II) complexes	None	None	View
Scopus	2-s2.0-84908293274	Evaluation of the in vitro anticancer activity of cyclometalated half-sandwich rhodium and iridiu...	Sudding L.C., Payne R., Govender P., Edafe F., Clavel C.M., Dyson P.J., Therrien B., Smith G.S.	2014	Journal of Organometallic Chemistry	774	None	10.1016/j.jorganchem.2014.10.003	Department of Chemistry, University of Cape Town, Private Bag, Rondebosch, South Africa; Institut...	Sudding, L.C., Department of Chemistry, University of Cape Town, Private Bag, Rondebosch, South A...	The development of cyclometalated rhodium and iridium complexes from first- and second-generation...	Anticancer drugs; Bioorganometallic chemistry; Cyclometalated; Iridium; Metallodendrimers; Rhodium	Rhodium; Anticancer activities; Anticancer drug; Bio-organometallic chemistry; Cyclometalated; Ha...	66054, National Research Foundation	View
Scopus	2-s2.0-84872721184	Synthesis, characterization, and pharmacological evaluation of silicon-containing aminoquinoline ...	Li Y., De Kock C., Smith P.J., Guzgay H., Hendricks D.T., Naran K., Mizrahi V., Warner D.F., Chib...	2013	Organometallics	32	1	10.1021/om300945c	Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Department of Me...	Li, Y., Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; De Kock,...	Two silicon-containing analogues (1, 2) of chloroquine, modified in the lateral side chain with o...	None	Aminoquinoline; Anti-mycobacterial; Anti-tumors; Cancer cell lines; Dinuclear; Half-sandwich; In-...	None	View
Scopus	2-s2.0-84883446453	Synthesis, characterization, antiparasitic and cytotoxic evaluation of thioureas conjugated to po...	Stringer T., Taylor D., De Kock C., Guzgay H., Au A., An S.H., Sanchez B., O'Connor R., Patel N.,...	2013	European Journal of Medicinal Chemistry	69	None	10.1016/j.ejmech.2013.08.004	Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Division of Phar...	Stringer, T., Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Ta...	A series of mono- and multimeric 4-amino-7-chloroquinoline and ferrocenyl thioureas have been pre...	β-Hematin inhibition; Antiparasitic activity; Antitumor activity; Ferrocene; Polyamines; Quinolin...	antineoplastic agent; antiprotozoal agent; beta hematin; chloroquine; cisplatin; ferrocene; hemat...	None	View
Scopus	2-s2.0-77955664975	Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity	Khanye S.D., Smith G.S., Lategan C., Smith P.J., Gut J., Rosenthal P.J., Chibale K.	2010	Journal of Inorganic Biochemistry	104	10	10.1016/j.jinorgbio.2010.06.005	Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Division of Phar...	Khanye, S.D., Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Sm...	The reaction of thiosemicarbazones (TSCs) with [AuI(THT)Cl], THT=tetrahydrothiophene, has been in...	Falcipain-2; Gold(I) complexes; P. falciparum; Thiosemicarbazones	chloroquine; n [n (3 carboxyoxirane 2 carbonyl)leucyl]agmatine; tetrahydrothiophene derivative; a...	None	View
Scopus	2-s2.0-55949121913	Reversed chloroquines based on the 3,4-dihydropyrimidin-2(1H)-one scaffold: Synthesis and evaluat...	October N., Watermeyer N.D., Yardley V., Egan T.J., Ncokazi K., Chibale K.	2008	ChemMedChem	3	11	10.1002/cmdc.200800172	Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Institute of Inf...	October, N., Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Wat...	(Chemical Equation Presented) The synthesis, cytotoxicity, and antimalarial activity of resistanc...	Dihydropyrimidinones; Drug design; Quinoline-containing antimalarials; Reversing agents; Sensitizers	antimalarial agent; chloroquine; hemoprotein; hemozoin; pyrimidine derivative; animal; article; b...	None	View
Scopus	2-s2.0-84867237053	The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation ...	Tukulula M., Little S., Gut J., Rosenthal P.J., Wan B., Franzblau S.G., Chibale K.	2012	European Journal of Medicinal Chemistry	57	None	10.1016/j.ejmech.2012.08.047	Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; London School of...	Tukulula, M., Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Li...	A series of new arylamino quinoline derivatives was designed based on the quinine and mefloquine ...	Antimycobacterial; Antiplasmodial; Arylamino quinoline tetrazoles; Physico-chemical properties	4 [(1 tert butyl 1h tetrazol 5 yl)(piperidin 1 yl)methyl] 6 methoxyquinoline; antimalarial agent;...	None	View
Scopus	2-s2.0-84925457770	Synthesis, characterization and evaluation of fluorocarbon-containing rhodium(I) complexes for bi...	Maqeda L., Makhubela B.C.E., Smith G.S.	2015	Polyhedron	91	None	10.1016/j.poly.2015.02.037	Department of Chemistry, University of Cape Town, Rondebosch, Cape Town, South Africa	Maqeda, L., Department of Chemistry, University of Cape Town, Rondebosch, Cape Town, South Africa...	Abstract A series of fluorocarbon-containing salicylaldimine and iminophosphine Schiff base ligan...	Biphasic catalysis; Fluorocarbon; Hydroformylation; Rhodium(I) complexes; Schiff bases	None	DST, University of Capetown; UCT, University of Capetown	View
Scopus	2-s2.0-84908026839	Synthesis and evaluation of a carbosilane congener of ferroquine and its corresponding half-sandw...	Li Y., De Kock C., Smith P.J., Chibale K., Smith G.S.	2014	Organometallics	33	17	10.1021/om500622p	Department of Chemistry, University of Cape Town, Rondebosch, South Africa; Department of Medicin...	Li, Y., Department of Chemistry, University of Cape Town, Rondebosch, South Africa; De Kock, C., ...	A silicon-containing congener of ferroquine (1) was synthesized by incorporating an organosilicon...	None	None	None	View
Scopus	2-s2.0-84938919085	Polyamine quinoline rhodium complexes: Synthesis and pharmacological evaluation as antiparasitic ...	Stringer T., Taylor D., Guzgay H., Shokar A., Au A., Smith P.J., Hendricks D.T., Land K.M., Egan ...	2015	Dalton Transactions	44	33	10.1039/c5dt02378e	Department of Chemistry, University of Cape Town, Rondebosch, South Africa; Division of Clinical ...	Stringer, T., Department of Chemistry, University of Cape Town, Rondebosch, South Africa; Taylor,...	A series of mono- and bis-salicylaldimine ligands and their corresponding Rh(i) complexes were pr...	None	Cells; Diseases; Ligands; Mass spectrometry; Rhodium; Strain; Synthesis (chemical); Antiparasitic...	Medical Research Council; MRC, Medical Research Council	View
Scopus	2-s2.0-84929463566	Synthesis, characterization and pharmacological evaluation of ferrocenyl azines and their rhodium...	Stringer T., Guzgay H., Combrinck J.M., Hopper M., Hendricks D.T., Smith P.J., Land K.M., Egan T....	2015	Journal of Organometallic Chemistry	788	None	10.1016/j.jorganchem.2015.04.009	Department of Chemistry, University of Cape Town, Rondebosch, South Africa; Division of Medical B...	Stringer, T., Department of Chemistry, University of Cape Town, Rondebosch, South Africa; Guzgay,...	Ferrocenyl azines containing salicylaldimine motifs were prepared by Schiff-base condensation of ...	Antiparasitic activity; Bioorganometallic chemistry; Cytotoxicity; Ferrocene; Heterobimetallic; P...	Cytotoxicity; Functional groups; Metallic compounds; Nitrogen compounds; Organometallics; Rhodium...	National Research Foundation	View
Scopus	2-s2.0-29144493144	Improving performance in a second year chemistry course: An evaluation of a tutorial scheme on th...	Davidowitz B., Rollnick M.	2005	South African Journal of Chemistry	58	None	None	Department of Chemistry, University of Cape Town, South Africa; School of Education, University o...	Davidowitz, B., Department of Chemistry, University of Cape Town, South Africa; Rollnick, M., Sch...	Throughput of students is a concern for academic departments especially since it will be the basi...	Chemical education; Curriculum design; Improving performance in chemistry; Tutorials	None	None	View
Scopus	2-s2.0-84890948686	Evaluation of (2-hydroxyethyl) triphenyl phosphonium bromide as corrosion inhibitor for mild stee...	Vashisht H., Kumar S., Bahadur I., Singh G.	2014	International Journal of Electrochemical Science	9	2	None	Department of Chemistry, University of Delhi, Delhi -110007, India; Thermodynamics Research Unit,...	Vashisht, H., Department of Chemistry, University of Delhi, Delhi -110007, India; Kumar, S., Depa...	The inhibition effect of the (2-Hydroxyethyl) triphenyl phosphonium bromide (HETPB) on mild steel...	Adsorption isotherms; Corrosion inhibitors; Mild steel; Phosphonium compound; Sulfuric acid solution	None	None	View
Scopus	2-s2.0-84897845493	Evaluation of benzyl triphenyl phosphonium chloride as corrosion inhibitor for mild steel in phos...	Vashisht H., Bahadur I., Kumar S., Bhrara K., Ramjugernath D., Singh G.	2014	International Journal of Electrochemical Science	9	6	None	Department of Chemistry, University of Delhi, Delhi-110007, India; Thermodynamics Research Unit, ...	Vashisht, H., Department of Chemistry, University of Delhi, Delhi-110007, India; Bahadur, I., The...	The effect of Benzyl triphenyl phosphonium chloride (BTPPC) on the corrosion of mild steel in a s...	Benzyltriphenylphosphonium chloride; Electrochemical impedance spectroscopy (EIS); Potentiodynami...	None	None	View
Scopus	2-s2.0-84945926134	Ru(II) and Co(II) complexes of bis(pyrazolyl)pyridine and pyridine-2,6-dicarboxylic acid: Synthes...	Motaung M.P., Ajibade P.A.	2015	International Journal of Electrochemical Science	10	10	None	Department of Chemistry, University of Fort Hare, Private Bag X1314, Alice, South Africa	Motaung, M.P., Department of Chemistry, University of Fort Hare, Private Bag X1314, Alice, South ...	We report the synthesis of two nitrogen chelating ligands: 2,6-bis(pyrazolyl)pyridine (L1); 2,6-b...	Conversion efficiency; Dye sensitizer; Dye-sensitized solar cells; Electrochemistry; Photo physic...	None	None	View
Scopus	2-s2.0-84876371789	Evaluation of oxine-type ligand coordination to zirconium (IV)	Steyn M., Visser H.G., Roodt A.	2013	Journal of the Southern African Institute of Mining and Metallurgy	113	2	None	Department of Chemistry, University of Free State, South Africa	Steyn, M., Department of Chemistry, University of Free State, South Africa; Visser, H.G., Departm...	[Zr(C9H6NO)4]·(HCON(CH 3)2)·(H2O), where (C9H 6NO) = 8-hydroxy quinoline (oxH), was synthesized a...	Quinolinato; Tetrakis coordination; Zirconium	Coordination polyhedra; Intermolecular interactions; Ligand coordination; Molecular entities; Qui...	None	View
Scopus	2-s2.0-56749160093	Impacts of natural and anthropogenic multiple sources of pollution on the environmental condition...	Adebowale K.O., Agunbiade F.O., Olu-Owolabi B.I.	2008	Electronic Journal of Environmental, Agricultural and Food Chemistry	7	4	None	Department of Chemistry, University of Ibadan, Ibadan, Nigeria	Adebowale, K.O., Department of Chemistry, University of Ibadan, Ibadan, Nigeria; Agunbiade, F.O.,...	The pollution status of the coastal water of Ondo State, Nigeria was investigated and found to be...	Anthropogenic activities; Metals; Ondo Coast; PCA; Pollution; Water quality	None	None	View
Scopus	2-s2.0-84875014784	Impact of effluent of an industrial estate on Oruku River in Southwestern Nigeria	Etim E.U., Onianwa P.C.	2013	World Applied Sciences Journal	21	7	10.5829/idosi.wasj.2013.21.7.1925	Department of Chemistry, University of Ibadan, Nigeria	Etim, E.U., Department of Chemistry, University of Ibadan, Nigeria; Onianwa, P.C., Department of ...	The impact of industrial effluent on the Oruku River in southwestern region of Nigeria was invest...	Groundwater; Heavy metals; Industrial effluent; Sediment; Surface water	None	None	View
Scopus	2-s2.0-70449333332	Impact of brewery effluent on water quality of the Olosun river in Ibadan, Nigeria	Ipeaiyeda A.R., Onianwa P.C.	2009	Chemistry and Ecology	25	3	10.1080/02757540902970314	Department of Chemistry, University of Ibadan, Ibadan, Nigeria	Ipeaiyeda, A.R., Department of Chemistry, University of Ibadan, Ibadan, Nigeria; Onianwa, P.C., D...	There has been significant pollution of the Olosun river in Ibadan with untreated brewery effluen...	Brewery effluent; Olosun river; Physicochemical impact; Water pollution; Water quality	ammonia; chloride; dissolved oxygen; effluent; nitrate; pH; physicochemical property; pollutant s...	None	View

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