Evaluation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa
Journal of Clinical Microbiology
Zambia AIDS Related Tuberculosis (ZAMBART), University of Zambia, School of Medicine, Lusaka, Zambia; London School of Hygiene and Tropical Medicine, University of London, London, United Kingdom; DST/NRF Centre of Excellence for Biomedical TB Research, Department of Biomedical Sciences, Stellenbosch University, Tygerberg, South Africa; Desmond Tutu TB Centre, Stellenbosch University, Tygerberg, South Africa
The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings. Copyright © 2010, American Society for Microbiology. All Rights Reserved.
article; bacterium culture; bacterium identification; bioassay; capilia TB assay; cost utility analysis; culture technique; liquid culture; Mycobacterium; Mycobacterium abscessus; Mycobacterium avium; Mycobacterium fortuitum; Mycobacterium gordonae; Mycobacterium interjectum; Mycobacterium intracellulare; Mycobacterium kansasii; Mycobacterium malmoense; Mycobacterium peregrinum; Mycobacterium scrofulaceum; Mycobacterium tuberculosis; nonhuman; priority journal; sensitivity and specificity; South Africa; tuberculosis; Zambia; Bacteriological Techniques; Humans; Mycobacterium tuberculosis; Sensitivity and Specificity; South Africa; Time Factors; Tuberculosis; Zambia; Mycobacterium tuberculosis