Gupta D.K., Tripathi A.K., Rajora V.S., Gupta G.C., Shukla S.K.
Govind Bhallabh Pant University of Agriculture and Technology, Pantnagar, Uttarakhand 263 145, India; GADVASU, Ludhiana 141 004, India; Department of Clinical Medicine, College of Veterinary and Animal Sciences; Addis Ababa University, Ethiopia
Gupta, D.K., Govind Bhallabh Pant University of Agriculture and Technology, Pantnagar, Uttarakhand 263 145, India, GADVASU, Ludhiana 141 004, India; Tripathi, A.K., Govind Bhallabh Pant University of Agriculture and Technology, Pantnagar, Uttarakhand 263 145, India, Department of Clinical Medicine, College of Veterinary and Animal Sciences; Rajora, V.S., Govind Bhallabh Pant University of Agriculture and Technology, Pantnagar, Uttarakhand 263 145, India, Department of Clinical Medicine, College of Veterinary and Animal Sciences; Gupta, G.C., Govind Bhallabh Pant University of Agriculture and Technology, Pantnagar, Uttarakhand 263 145, India, Addis Ababa University, Ethiopia; Shukla, S.K., Govind Bhallabh Pant University of Agriculture and Technology, Pantnagar, Uttarakhand 263 145, India, GADVASU, Ludhiana 141 004, India
The antioxidative potential of hydro-alcoholic extracts of Ocimum sanctum (tulsi) and Emblica officinalis (amla) was assessed in normal and immune-compromised rats. The extracts were given @ 100 mg/kg b.wt. daily po for 21 days and cyclophosphamide was administered intraperitonially @ 50 mg/kg once at the start of expeiriment. The lipid peroxidation (LPO), reduced glutathione (GSH) content, superoxide dismutase (SOD) and catalase (CAT) activities were assessed. On the basis of results, it was concluded that Ocimum sanctum and Emblica officinalis both are not only useful in controlling the lipid peroxide levels but are also helpful in further strengthening the antioxidant potential, however, Emblica officinalis was superior to Ocimum sanctum.
