Department of Veterinary Medicine, University of Cambridge, CB3 OES, Cambridge, United Kingdom; Department of Applied Mathematics, Modeling Biomedical Systems Research Group, National University of Science and Technology, Bulawayo, Zimbabwe
Bhunu, C.P., Department of Veterinary Medicine, University of Cambridge, CB3 OES, Cambridge, United Kingdom, Department of Applied Mathematics, Modeling Biomedical Systems Research Group, National University of Science and Technology, Bulawayo, Zimbabwe
Human rabies cases are not declining in Africa and Asia even though possible interventions are available. A mathematical model for the transmission dynamics of rabies is presented and analyzed in the presence of intervention strategies (culling, dog vaccinations, pre- and post-exposure vaccinations for humans). The reproduction number is computed and rigorously analyzed. Analytical results suggest that the key to rabies control lies in good animal control and seeking medical advice early, once exposed to a dog bite. Numerical simulations support analytical results obtained. We conclude that the post-exposure prophylaxis might be the best possible way to control rabies in developing nations if it can be made easily accessible to those in need. However, due to costs of vaccines which are beyond the reach of many people in developing nations, it may be best to come up with better animal control strategies to control the spread of rabies. © 2011 World Scientific Publishing Company.
