Department of Medical Laboratory Science, Faculty of Basic Medical Science, College of Health Sciences, Niger Delta University, Wilberforce Island, P.M.B. 071 Yenagoa, Bayelsa State, Nigeria; Department of Human Anatomy, Faculty of Basic Medical Science,
Ilegbedion, I.G., Department of Medical Laboratory Science, Faculty of Basic Medical Science, College of Health Sciences, Niger Delta University, Wilberforce Island, P.M.B. 071 Yenagoa, Bayelsa State, Nigeria; Onyije, F.M., Department of Human Anatomy, Faculty of Basic Medical Science, College of Health Sciences, Niger Delta University, Wilberforce Island, P.M.B. 071 Yenagoa, Bayelsa State, Nigeria; Digba, K.A., Department of Medical Laboratory Science, Faculty of Health Sciences, Igbinedion University, Okada, Edo State, Nigeria
Commercial MSG is produced by fermentation of starch, sugar, beet, sugarcane or molasses. It is one of the main flavor enhancer used as an ingredient in various food products. Its palatable and favorite flavor is a must in almost all Chinese, South-Asian and Nigerian dishes, where it is known by the names of Ajinomoto and white-Maggi.Twenty (20) female adult wistar rats were used for this experiment. The rats with average weight of 181g were randomly assigned into four groups of five each (Groups A, B, C and O). Group A, B and C served as treatments groups while group O as the control. Each rat in the treatment groups A, B and C received 0.1, 0.15 and 0.20 g kg-1 of monosodium glutamate. Results showed that there was elevation ofK+ in groups A and C (6.42 ± 0.40 and 6.07 ± 59) but was not statistically found different from control. While there was a significant elevation of Na+ in group A (0. lg kg-1), Cl' in group C (0.20g kg-1), Ca2+ in group B, TCa in both groups A and B and pH also increased significantly in group C. In the method used there were no notable distortions of the mucosa architecture of the tissues. Research on MSG should go beyond rudimentary to advance molecular since much have been done on the basic, hoping that the molecular advancement will help to establish clearly what MSG can do to human © IDOSI Publications, 2013.
