Renner L.A., Newman M.J., Ahadzie L., Antwi-Agyei K.O., Eshetu M.
Department of Child Health, University of Ghana Medical School, Accra, Ghana; Department of Microbiology, University of Ghana Medical School, Accra, Ghana; Disease Surveillance Unit, Ghana Health Service, Ministry of Health, Accra, Ghana; EPI Unit, Ghana Health Service, Ministry of Health, Accra, Ghana; WHO, Nairobi, Kenya
Renner, L.A., Department of Child Health, University of Ghana Medical School, Accra, Ghana; Newman, M.J., Department of Microbiology, University of Ghana Medical School, Accra, Ghana; Ahadzie, L., Disease Surveillance Unit, Ghana Health Service, Ministry of Health, Accra, Ghana; Antwi-Agyei, K.O., EPI Unit, Ghana Health Service, Ministry of Health, Accra, Ghana; Eshetu, M., WHO, Nairobi, Kenya
This report shows the impact of a pentavalent vaccine that includes Haemophilus influenzae type b (Hib) conjugate vaccine on bacterial meningitis in children younger than 5 years in Ghana. A review of the first 3 years of a pediatric bacterial meningitis surveillance program, started in August 2001 in Accra, Ghana, was undertaken. There was a significant reduction, P = 0.042 and 0.017, in percentage of purulent meningitis in children younger than 1 year, comparing the first year when the vaccine was introduced, to the second and third years, respectively. © 2007 Lippincott Williams & Wilkins, Inc.
Haemophilus influenzae type b vaccine; article; bacterial meningitis; bacterium culture; cerebrospinal fluid analysis; controlled study; Ghana; health survey; human; immunization; infant; lumbar puncture; major clinical study; medical record; mortality; preschool child; priority journal; Child, Preschool; Ghana; Haemophilus influenzae type b; Haemophilus Vaccines; Humans; Immunization Programs; Incidence; Infant; Meningitis, Bacterial; Meningitis, Haemophilus; Neisseria meningitidis; Streptococcus pneumoniae; Vaccines, Conjugate