Evaluation of phytochemicals and antioxidants of four botanicals with antihypertensive properties
International Journal of Pharma and Bio Sciences
Department of Biochemistry, University of Ado-Ekiti, Nigeria; Department of Chemistry, University of Ado-Ekiti, Nigeria
Evaluation of phytochemicals and antioxidants levels were conducted in the dry leaves of aqueous and methanolic extracts of Vernonia amygdalina, Carica papaya, Persea americana and Cnidosculous aconitifolius. Methanolic extract was found to contain the highest value for sterols, tannin, saponin, flavonoids, alkaloids, phenols, phlobatannins, anthraquinones, triterpenes and cardiac glycosides. However, oxalate and phytate were absent in both aqueous and methanolic extracts. The results also showed that leave extracts of these plants are good sources of antioxidants as revealed by the presence of these antioxidants in these plant but with highest values in the methanolic extract. Conclusively, the presence of some of these phytochemicals and antioxidants explained the hypotensive action of these plants in cardiovascular diseases.
alkaloid; alpha tocopherol; anthraquinone derivative; antihypertensive agent; antioxidant; ascorbic acid; cardiac glycoside; Carica papaya extract; carotene; catalase; Cnidoscolous aconitifolius extract; flavonoid; glutathione peroxidase; methanol; oxalic acid; Persea americana extract; phenol derivative; phlobatannin; phytate; phytosterol; plant extract; saponin; sterol; tannin; tannin derivative; triterpene; unclassified drug; Vernonia amygdalina extract; antihypertensive activity; antioxidant activity; article; avocado; biocatalysis; cardiovascular disease; Cnidoscolous aconitifolius; concentration (parameters); controlled study; drug determination; drug screening; enzyme activity; oxidative stress; papaya; phytochemistry; plant leaf; shrub; Vernonia; vernonia amygdalina