African Evaluation Database

9120 records found

Source	Electronic ID	Title	Authors	Publication Year	Source Title	Volume	Issue	DOI	Affiliations	Authors with Affiliations	Abstract	Author Keywords	Index Keywords▼	Funding Details
Scopus	2-s2.0-84887429406	Evaluation of Baylis-Hillman Routes to 3-(Aminomethyl)coumarin Derivatives	Olasupo I., Rose N.R., Klein R., Adams L.A., Familoni O.B., Kaye P.T.	2014	Synthetic Communications	44	2	10.1080/00397911.2013.803575	Department of Chemistry, University of Lagos, Lagos, Nigeria; Department of Chemistry and Center ...	Olasupo, I., Department of Chemistry, University of Lagos, Lagos, Nigeria; Rose, N.R., Department...	The relative merits of two different Baylis-Hillman approaches toward the preparation of coumarin...	3-(Aminomethyl)coumarins; aza-Michael; Baylis-Hillman	3 (aminomethyl)coumarin derivative; acrylic acid butyl ester; acrylic acid methyl ester; coumarin...	62273, National Research Foundation	View
Scopus	2-s2.0-76149091240	Microwave-assisted synthesis and evaluation of antimicrobial activity of 3-{3-(s-aryl and s-heter...	Ajani O.O., Nwinyi O.C.	2010	Journal of Heterocyclic Chemistry	47	1	10.1002/jhet.298	Chemistry Department, College of Science and Technology, Covenant University, Ota, Ogun State, Ni...	Ajani, O.O., Chemistry Department, College of Science and Technology, Covenant University, Ota, O...	(Chemical Equation Presented) The exploration of potential utilization of microwaves as an energy...	None	3 (5 phenylpenta 2,4 dienoyl) 2h chromen 2 one; 3 [3 (3 hydroxyphenyl)acryloyl] 2h chromen 2 one;...	None	View
Scopus	2-s2.0-84855999356	Structure-based design, synthesis and biological evaluation of N-pyrazole, N′-thiazole urea inhib...	Getlik M., Grütter C., Simard J.R., Nguyen H.D., Robubi A., Aust B., Van Otterlo W.A.L., Rauh D.	2012	European Journal of Medicinal Chemistry	48	None	10.1016/j.ejmech.2011.11.019	Chemical Genomics Centre of the Max Planck Society, Otto-Hahn-Strasse 15, D-44227 Dortmund, Germa...	Getlik, M., Chemical Genomics Centre of the Max Planck Society, Otto-Hahn-Strasse 15, D-44227 Dor...	In this paper, we present the structure-based design, synthesis and biological activity of N-pyra...	DFG-out; Kinase inhibitors; p38α MAPK	[3 [5 [[[[4 [2 (benzyloxy)ethyl] 1,3 thiazol 2 yl]amino]carbonyl]amino] 3 cyclopentyl 1h pyrazol ...	None	View
Scopus	2-s2.0-80455137096	Isolation of 3-(4-hydroxyphenyl) methylpropenoate and bioactivity evaluation of Gomphrena celosio...	Dosumua O.O., Idowuc P.A., Onochab P.A., Ekundayob O.	2010	EXCLI Journal	9	None	None	Department of Chemistry, University of Ilorin, Ilorin, Nigeria; Department of Chemistry, Universi...	Dosumua, O.O., Department of Chemistry, University of Ilorin, Ilorin, Nigeria; Idowuc, P.A., Depa...	The efficacy of Gomphrena celosioides extracts in traditional medicine in the treatment of infect...	Anthelmintic; Antimicrobial; Cytotoxicity; Gomphrena celosioides; Phytochemical analysis	3 (4 hydroxyphenyl)methylpropenate; acetic acid ethyl ester; ampicillin; anthelmintic agent; anti...	None	View
Scopus	2-s2.0-77953635043	Evaluation of seven tests for the rapid detection of multidrug-resistant tuberculosis in Uganda	Bwanga F., Joloba M.L., Haile M., Hoffner S.	2010	International Journal of Tuberculosis and Lung Disease	14	7	None	Department of Medical Microbiology, College of Health Sciences, Makerere University, Kampala, Uga...	Bwanga, F., Department of Medical Microbiology, College of Health Sciences, Makerere University, ...	SETTINGS: National Tuberculosis (TB) Reference Laboratory and Department of Medical Microbiology,...	Drug susceptibility testing; Drug-resistant tuberculosis; M. tuberculosis; MDR-TB	3 (4,5 dimethyl 2 thiazolyl) 2,5 diphenyltetrazolium bromide; isoniazid; nitrate reductase; resaz...	None	View
Scopus	2-s2.0-79959853538	Cytotoxicity evaluation of selected Nigerian plants used in traditional cancer treatment	Sowemimo A., ven de Venter M., Baatjies L., Koekemoer T.	2011	Journal of Medicinal Plants Research	5	11	None	Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, College of Medicine Campus...	Sowemimo, A., Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, College of M...	Herbal medicines have received much attention as a source of new anticancer drugs. However, scien...	Cancer; Cisplatin; Cytotoxicity; Sapium; Traditional medicine	3 (4,5 dimethyl 2 thiazolyl) 2,5 diphenyltetrazolium bromide; antineoplastic agent; Celosia trigy...	None	View
Scopus	2-s2.0-84920506835	Evaluation of halogenated coumarins for antimosquito properties	Narayanaswamy V.K., Gleiser R.M., Kasumbwe K., Aldhubiab B.E., Attimarad M.V., Odhav B.	2014	Scientific World Journal	2014	None	10.1155/2014/189824	Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-A...	Narayanaswamy, V.K., Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Fa...	Mosquitoes are the major vectors of parasites and pathogens affecting humans and domestic animals...	None	3 (2 aminothiazol 4 yl) 6 bromo 2h chromen 2 one; 3 (2 bromoacetyl) 2h chromen 2 one; 3 (2 bromoa...	None	View
Scopus	2-s2.0-79955583128	Expeditious synthesis and biological evaluation of novel 2,N 6-disubstituted 1,2-dihydro-1,3,5-tr...	Gravestock D., Rousseau A.L., Lourens A.C.U., Moleele S.S., Van Zyl R.L., Steenkamp P.A.	2011	European Journal of Medicinal Chemistry	46	6	10.1016/j.ejmech.2011.02.054	Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johannesburg, South Af...	Gravestock, D., Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johann...	A small set of novel 2,N6-disubstituted 1,2-dihydro-1,3,5- triazine-4,6-diamines was prepared pos...	2,N6-Disubstituted 1,2-dihydro-1,3,5- triazine-4,6-diamine; Antimalarial; Biguanide; Cycloguanil;...	2 phenyl n 6 (3 (2,4,6 trichlorophenoxy)propyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; 4,6 diami...	None	View
Scopus	2-s2.0-84864351893	Saccharomyces cerevisiae oxidative response evaluation by cyclic voltammetry and gas chromatograp...	Castro C.C., Gunning C., Oliveira C.M., Couto J.A., Teixeira J.A., Martins R.C., Ferreira A.C.S.	2012	Journal of Agricultural and Food Chemistry	60	29	10.1021/jf300389v	IBB-Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, Universidad...	Castro, C.C., IBB-Institute for Biotechnology and Bioengineering, Centre of Biological Engineerin...	This study is focused on the evaluation of the impact of Saccharomyces cerevisiae metabolism in t...	Bioanalytical methods; chemometrics; electrochemical sensors; mass spectrometry	2-phenylethanol; Alcoholic fermentation; Antioxidant capacity; Bioanalytical; Bioanalytical metho...	None	View
Scopus	2-s2.0-84934764742	Biological activities of (E)-N-(CH<inf>3</inf>-substituted-phenyl)-1-phenylmethanimine: Evaluatio...	Mkpenie V.N., Mkpenie I.V., Essien E.E.	2015	Der Pharma Chemica	7	6	None	Department of Chemistry, University of Uyo, Uyo, Nigeria	Mkpenie, V.N., Department of Chemistry, University of Uyo, Uyo, Nigeria; Mkpenie, I.V., Departmen...	Schiff bases with ortho-, meta- and para-methyl substituents were synthesized by thecondensation ...	Antibacterial activity; Antifungal activity; Schiff bases; Substitution effect; Toluidine	2 methylaniline; 3 methylaniline; 4 methylaniline; aniline derivative; antiinfective agent; benza...	None	View
Scopus	2-s2.0-84919947877	Synthesis of functionalized 3-, 5-, 6- and 8-aminoquinolines via intermediate (3-pyrrolin-1-yl)- ...	Vandekerckhove S., Van Herreweghe S., Willems J., Danneels B., Desmet T., De Kock C., Smith P.J.,...	2015	European Journal of Medicinal Chemistry	92	None	10.1016/j.ejmech.2014.12.020	SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Ghent Univers...	Vandekerckhove, S., SynBioC Research Group, Department of Sustainable Organic Chemistry and Techn...	(3-Pyrrolin-1-yl)- and (2-oxopyrrolidin-1-yl)quinolines were prepared via cyclization of diallyla...	Antimalarial agents; Antimicrobial agents; Pyrrolidine derivatives; Quinolines	2 methyl 3 (2 methylpyrrolidin 1 yl)quinoline; 3 (2 methylpyrrolidin 1 yl)quinoline; 3 (pyrrolidi...	None	View
Scopus	2-s2.0-35349012079	Development of an analytical method for the evaluation of N,N-dimethylformamide in dosage form de...	Olivier E.I., Du Toit D., Hamman J.H.	2007	Pharmazie	62	10	10.1691/ph.2007.10.7013	Department of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria, South Africa; ...	Olivier, E.I., Department of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria,...	N,N-Dimethylformamide (DMF) is a well-known chemical entity that is extensively used for pharmace...	None	2 methoxyethanol; macrogol; n,n dimethylformamide; article; chemical analysis; drug delivery syst...	None	View
Scopus	2-s2.0-84908161323	The impact of biochar on the bioaccessibility of 14C-phenanthrene in aged soil	Ogbonnaya O.U., Adebisi O.O., Semple K.T.	2014	Environmental Sciences: Processes and Impacts	16	11	10.1039/c4em00396a	EcoSystems Environmental Management Services Ltd, 8 Rasheed Alaba Williams Street, Off Admiralty ...	Ogbonnaya, O.U., EcoSystems Environmental Management Services Ltd, 8 Rasheed Alaba Williams Stree...	Biochar is a carbon rich product from the incomplete combustion of biomass and it has been shown ...	None	2 hydroxypropyl beta cyclodextrin; adsorbent; biochar; phenanthrene c 14; radioisotope; unclassif...	None	View
Scopus	2-s2.0-79651470475	Docking, Synthesis, and in vitro Evaluation of Antimitotic Estrone Analogs	Stander A., Joubert F., Joubert A.	2011	Chemical Biology and Drug Design	77	3	10.1111/j.1747-0285.2010.01064.x	Department of Physiology, University of Pretoria, Pretoria, South Africa; Department of Biochemis...	Stander, A., Department of Physiology, University of Pretoria, Pretoria, South Africa; Joubert, F...	In the present study, Autodock 4.0 was employed to discover potential carbonic anhydrase IX inhib...	Biological screening; Mechanism-based drug design; Virtual screening	2 ethyl 3 o sulphamoy lestra 1,3,5(10), 15 tetraen 3 ol 17 one estronem; 2 ethyl 3 o sulphamoyl e...	None	View
Scopus	2-s2.0-84871669146	In Vitro Evaluation of ESE-15-ol, an Estradiol Analogue with Nanomolar Antimitotic and Carbonic A...	Stander B.A., Joubert F., Tu C., Sippel K.H., McKenna R., Joubert A.M.	2012	PLoS ONE	7	12	10.1371/journal.pone.0052205	Department of Physiology, University of Pretoria, Pretoria, Gauteng, South Africa; Department of ...	Stander, B.A., Department of Physiology, University of Pretoria, Pretoria, Gauteng, South Africa;...	Antimitotic compounds are still one of the most widely used chemotherapeutic anticancer drugs in ...	None	2 ethyl 3 o sulphamoyl estra 1,3,5(10),15 tetraen 17 ol; antineoplastic agent; carbonate dehydrat...	None	View
Scopus	2-s2.0-84884937244	Imino-phosphine palladium(II) and platinum(II) complexes: Synthesis, molecular structures and eva...	Motswainyana W.M., Onani M.O., Madiehe A.M., Saibu M., Thovhogi N., Lalancette R.A.	2013	Journal of Inorganic Biochemistry	129	None	10.1016/j.jinorgbio.2013.09.010	Chemistry Department, University of the Western Cape, Private Bag X17, Bellville 7535, South Afri...	Motswainyana, W.M., Chemistry Department, University of the Western Cape, Private Bag X17, Bellvi...	The imino-phosphine ligands L1 and L2 were prepared via condensation reaction of 2-(diphenylphosp...	Antitumor; Imino-phosphine; Molecular structures; Palladium; Platinum; Synthesis	(2 diphenylphosphino benzylidene) 2 methylphenylen amine; (2 diphenylphosphino benzylidene) 2,6 d...	National Research Foundation	View
Scopus	2-s2.0-84884354676	Ozone facilitated dechlorination of 2-chloroethanol and impact of organic solvents and activated ...	Gounden A.N., Jonnalagadda S.B.	2013	Environmental Monitoring and Assessment	185	10	10.1007/s10661-013-3169-4	Department of Chemistry, Mangosuthu University of Technology, P.O. Box 12363, Jacobs 4026, South ...	Gounden, A.N., Department of Chemistry, Mangosuthu University of Technology, P.O. Box 12363, Jaco...	The ozone-initiated oxidation of 2-chloroethanol was followed by monitoring the consumption of th...	Acetaldehyde; Acetic acid; Chloride ion; Dechlorination; Ozonation	2-Chloroethanol; Chloride ions; Ethyl acetates; Organic substrate; Ozone treatment; Solvent free;...	None	View
Scopus	2-s2.0-84868307948	Synthesis and antimicrobial evaluation of some novel substituted 2-chloroacetanalides	Aschale M.	2012	International Journal of ChemTech Research	4	4	None	Head of Chemistry Department, College of Natural and Computation Sciences, Haramaya University, E...	Aschale, M., Head of Chemistry Department, College of Natural and Computation Sciences, Haramaya ...	The title compounds were prepared by the reaction of substituted primary amines with chloroacetyl...	Antibacterial; Antifungal; Substituted chloroacetinilides	2 chloroacetanilide; 2 iodo 2 chloroacetanilide; 3 bromo 2 chloroacetanilide; 3 chloro 2 chloroac...	None	View
Scopus	2-s2.0-84929992950	Synthesis and evaluation of the antiplasmodial activity of tryptanthrin derivatives	Onambele L.A., Riepl H., Fischer R., Pradel G., Prokop A., Aminake M.N.	2015	International Journal for Parasitology: Drugs and Drug Resistance	5	2	10.1016/j.ijpddr.2015.03.002	Institute of Molecular Biotechnology, RWTH Aachen University, Aachen, Germany; HochschuleWeihenst...	Onambele, L.A., Institute of Molecular Biotechnology, RWTH Aachen University, Aachen, Germany; Ri...	Malaria remains one of the most deadly diseases threatening humankind and is still affecting a si...	Antiplasmodial; Gametocytes; Malaria; Synthesis; Tryptanthrin derivatives	2 chloro 8 bromo tryptanthrin 8 bromo 2 chloro indolo[2,1 b]quinazoline 6,12 dione; 2 chloro 8 ni...	None	View
Scopus	2-s2.0-84901813929	Genotoxicity evaluation of 4-carboxyl- 2,6- dinitrophenylazohydroxynaphthalenes in mice	Adegoke O.A., Ghosh M., Manivannan J., Sinha S., Mukherjee A.	2014	Toxicology and Industrial Health	30	5	10.1177/0748233712457442	Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ibadan, Orita UI, Ibad...	Adegoke, O.A., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ibadan,...	A short-term in vivo genotoxicity evaluation of 4-carboxyl-2,6- dinitrophenylazohydronaphthalenes...	4-Carboxyl-2; 6-dinitrophenylazohydroxynaphthalenes; azo-hydrazone tautomerism; chromosomal aberr...	2 butanone; 4 [(2 hydroxynapthalen 1 yl)diazenyl] 3,5 dinitrobenzoic acid; 4 [(4 hydroxynaphthale...	None	View

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