African Evaluation Database

9120 records found

Source	Electronic ID	Title	Authors	Publication Year	Source Title	Volume	Issue	DOI	Affiliations	Authors with Affiliations	Abstract	Author Keywords	Index Keywords▼	Funding Details
Scopus	2-s2.0-84878098841	Preliminary structure - Activity relationships and biological evaluation of novel antitubercular ...	Onajole O.K., Pieroni M., Tipparaju S.K., Lun S., Stec J., Chen G., Gunosewoyo H., Guo H., Ammerm...	2013	Journal of Medicinal Chemistry	56	10	10.1021/jm4003878	Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois ...	Onajole, O.K., Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Universi...	Tuberculosis (TB) remains one of the leading causes of mortality and morbidity worldwide, with ap...	None	6,7 dihydro 2 nitro 6 (4 trifluoromethoxybenzyloxy) 5h imidazo[2,1 b][1,3]oxazine; bedaquiline; i...	None	View
Scopus	2-s2.0-84941642623	Evaluation of predictive CYP2C19 genotyping assays relative to measured phenotype in a South Afri...	Dodgen T.M., Drögemöller B.I., Wright G.E.B., Warnich L., Steffens F.E., Cromarty A.D., Alessandr...	2015	Pharmacogenomics	16	12	10.2217/pgs.15.80	Department of Pharmacology, University of Pretoria, Pretoria, South Africa; Department of Immunol...	Dodgen, T.M., Department of Pharmacology, University of Pretoria, Pretoria, South Africa, Departm...	Aim: To align predicted and measured CYP2C19 phenotype in a South African cohort. Materials & met...	activity score system; CYP2C19; genotype-phenotype correlation; omeprazole; South Africa	5' hydroxyomperazole; cytochrome P450 2C19; drug metabolite; omeprazole; unclassified drug; adult...	None	View
Scopus	2-s2.0-84876719611	Synthesis and antiplasmodial evaluation of aziridine-(iso)quinoline hybrids and their ring-openin...	Vandekerckhove S., De Moor S., Segers D., De Kock C., Smith P.J., Chibale K., De Kimpe N., D'Hoog...	2013	MedChemComm	4	4	10.1039/c3md20377h	Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Gh...	Vandekerckhove, S., Department of Sustainable Organic Chemistry and Technology, Faculty of Biosci...	Aziridine-(iso)quinoline hybrid systems were prepared as novel synthetic intermediates en route t...	None	5 hydroxyisoquinoline; antimalarial agent; aziridine(iso)quinoline derivative; chloroquine; metha...	None	View
Scopus	2-s2.0-84923339760	Preparative isolation of bio-markers from the leaf exudate of Aloe ferox ("aloe bitters") by high...	Adhami H.-R., Viljoen A.M.	2015	Phytochemistry Letters	11	None	10.1016/j.phytol.2014.07.001	Department of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria, South Africa	Adhami, H.-R., Department of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria,...	One of the most crucial factors determining the safety and efficacy of any herbal medicine or nat...	Aloe ferox; Aloeresin A; Aloesin; Aloin A and B; chromatography; High performance counter-current	5 hydroxyaloin; aloeresin a; aloeresin c; aloesin; aloin; aloinoside a; aloinoside b; biological ...	National Research Foundation	View
Scopus	2-s2.0-84887852698	Dyeing performance of aqueous extract and flavanone glycosides from the flowers of Butea monosper...	Semwal R.B., Semwal D.K., Badoni P.P., Kapoor P.	2014	Records of Natural Products	8	1	None	Department of Chemistry, Panjab University, Chandigarh-160014, India; Department of Pharmaceutica...	Semwal, R.B., Department of Chemistry, Panjab University, Chandigarh-160014, India, Department of...	Aqueous extract and two flavanone glycosides named 5,7-dihydroxy-4'-methoxy flavanone-5-β-D-gluco...	Butea monosperma; Flavanone glycosides; Light fastness; Myrica esculenta; Natural dyes	5,5' dihydroxy 4',7 dimethoxyflavanone 5,5' di o beta dextro glucopyranoside; 5,7 dihydroxy 4' me...	None	View
Scopus	2-s2.0-84904751635	Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents	Manda V.K., Dale O.R., Awortwe C., Ali Z., Khan I.A., Walker L.A., Khan S.I.	2014	Frontiers in Pharmacology	42556	None	10.3389/fphar.2014.00178	National Center for Natural Products Research, School of Pharmacy, The University of Mississippi,...	Manda, V.K., National Center for Natural Products Research, School of Pharmacy, The University of...	Labisia pumila (Kacip Fatimah) is a popular herb in Malaysia that has been traditionally used in ...	CYP450 enzymes; Herb-drug interactions; Labisia pumila; Myrsinaceae; P-gp; Pxr	5 (10pentadecenyl)resorcinol; alkylphenol derivative; ardisimamilloside H; belamcandol B; cyclosp...	U01-FD004246-01, FDA, U.S. Food and Drug Administration	View
Scopus	2-s2.0-33847627864	Methylenetetrahydrofolate reductase gene polymorphisms in Burkina Faso: Impact on plasma fasting ...	Angius A., Simpore J., Persico I., Sassu A., Prodi D.A., Musumeci S.	2007	Clinical Laboratory	53	42371	None	Institute of Population Genetics, CNR, Alghero, SS, Italy; Shardna Life Sciences, Cagliari, Italy...	Angius, A., Institute of Population Genetics, CNR, Alghero, SS, Italy, Shardna Life Sciences, Cag...	In Burkina Faso the levels of plasma homocysteine (Hcy) are lower and the methionine loading test...	A298C; Burkina Faso; C677T; Homocysteine; Methionine loading test; MTHFR	5,10 methylenetetrahydrofolate reductase (FADH2); homocysteine; methionine; adult; age distributi...	None	View
Scopus	2-s2.0-84897865091	The impact of microbial ecology and chemical profile on the enhanced biological phosphorus remova...	Kamika I., Coetzee M., Mamba B.B., Msagati T., Momba M.N.B.	2014	International Journal of Environmental Research and Public Health	11	3	10.3390/ijerph110302876	Department of Environmental, Water and Earth Sciences, Tshwane University of Technology, Arcadia ...	Kamika, I., Department of Environmental, Water and Earth Sciences, Tshwane University of Technolo...	The impact of polyphosphate-accumulating organism (PAO) and glycogen-accumulating organism (GAO) ...	EBPR; Glycogen-accumulating organisms; Polyphosphate-accumulating organisms; Volatile fatty acids...	4 methylpentanoic acid; acetic acid; fatty acid; glycogen; heptanoic acid derivative; isobutyric ...	None	View
Scopus	2-s2.0-77955274098	Evaluation of flavonoids from Dorstenia barteri for their antimycobacterial, antigonorrheal and a...	Kuete V., Ngameni B., Mbaveng A.T., Ngadjui B., Meyer J.J.M., Lall N.	2010	Acta Tropica	116	1	10.1016/j.actatropica.2010.06.005	Department of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Came...	Kuete, V., Department of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67, Ds...	The aim of this study was to evaluate the antimycobacterial, antigonorrheal and reverse transcrip...	Anti-reverse transcriptase; Antigonorrheal; Antimycobacterial; Dortenia barteri; Flavonoids	4 hydroxylonchocarpin; amentoflavone; Dorstenia barteri extract; flavonoid; isobachalcone; kanzan...	None	View
Scopus	2-s2.0-84881028983	Design of an anti-inflammatory composite nanosystem and evaluation of its potential for ocular dr...	Du Toit L.C., Govender T., Carmichael T., Kumar P., Choonara Y.E., Pillay V.	2013	Journal of Pharmaceutical Sciences	102	8	10.1002/jps.23650	Department of Pharmacy and Pharmacology, University of the Witwatersrand, Parktown, Johannesburg ...	Du Toit, L.C., Department of Pharmacy and Pharmacology, University of the Witwatersrand, Parktown...	This study compared two specific embodiments of an ocular nanosystem (NS): one portraying a purel...	Cell uptake; Computational modeling; Confocal microscopy; ELISA; Lipids; Liposomes; permeation; N...	4 chloro 7 nitrobenzofurazan; chitosan; ganciclovir; I kappa B; indometacin; liposome; nanopartic...	None	View
Scopus	2-s2.0-84905258580	Synthesis, anti-inflammatory and anti-nociceptive evaluation of palmitoyl benzamides	Baba H., Usifoh C.O., Igbinaduwa P.O.	2014	Tropical Journal of Pharmaceutical Research	13	7	10.4314/tjpr.v13i7.17	Department of Pharmaceutical and Medicinal Chemistry, Niger Delta University, Wilberforce Island,...	Baba, H., Department of Pharmaceutical and Medicinal Chemistry, Niger Delta University, Wilberfor...	Purpose: To synthesize and characterize palmitoyl amino benzamides, and to evaluate them for poss...	Analgesic; Anti-inflammatory; Aspirin; Benzamide; Glycine; Palmitoyl; β-Alanine; γ-Aminobutyric acid	4 aminobutyric acid; acetylsalicylic acid; benzamide derivative; beta alanine; glycine; o palmito...	None	View
Scopus	2-s2.0-84856567704	Evaluation of antibacterial potential of crude extract of Moringa oleifera seed on orthopaedics w...	Oluduro O.A., Idowu T.O., Aderiye B.I., Famurewa O., Omoboye O.O.	2012	Research Journal of Medicinal Plant	6	5	10.3923/rjmp.2012.383.394	Department of Microbiology, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Nigeria; Dep...	Oluduro, O.A., Department of Microbiology, Faculty of Science, Obafemi Awolowo University, Ile-If...	The antibacterial activity of crude aqueous and methanolic extracts of Moringa oleifera seed on s...	Antibacterial activity; Benzyl isothiocyanate derivative; Moringa; Phenylmethanamine; Seed	4 (alpha rhamnopyranosyloxyl)benzyl isothiocyanic acid; 4 hydroxyphenyl acetic acid; benzyl isoth...	None	View
Scopus	2-s2.0-38349191053	Comparative evaluation of the microbial community in biological processes treating industrial and...	Degenaar A.P., Ismail A., Bux F.	2008	Journal of Applied Microbiology	104	2	10.1111/j.1365-2672.2007.03563.x	Centre for Water and Wastewater Technology, Department of Biotechnology, Durban University of Tec...	Degenaar, A.P., Centre for Water and Wastewater Technology, Department of Biotechnology, Durban U...	Aims: Comparison of the microbial composition and process performance between laboratory scale pr...	Alpha-proteobacteria; Beta-proteobacteria; FISH; Vegetable oil effluent treatment	4',6 diamidino 2 phenylindole; nitrogen; vegetable oil; biodegradation; chemical oxygen demand; c...	None	View
Scopus	2-s2.0-33751566546	Cytotoxicity evaluation and isolation of a chroman derivative from Phyllanthus amarus aerial part...	Ajaiyeoba E., Kingston D.	2006	Pharmaceutical Biology	44	9	10.1080/13880200601006905	Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria; Chemistr...	Ajaiyeoba, E., Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan, Ni...	Chemical and cytotoxicity examinations of the crude methanol extract of the aerial parts of Phyll...	Aerial parts; Cancer cell; Chroman derivative; Cytotoxicity; Phyllanthus amarus	4,4,8 trimethoxychroman; chroman derivative; dactinomycin; dichloromethane; methanol; Phyllanthus...	None	View
Scopus	2-s2.0-84856430789	In vitro genotoxicity evaluation of 4-carboxyl-2,6-dinitrophenylazohydroxynaphthalenes using huma...	Adegoke O.A., Kyu J.K., Mukherjee A.	2012	Food and Chemical Toxicology	50	04-Mar	10.1016/j.fct.2011.11.022	Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ibadan, Nigeria; Korea...	Adegoke, O.A., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ibadan,...	The genotoxicity of a new monoazo dye series, 4-carboxyl-2,6-dinitrophenylazohydroxynaphthalenes ...	4-Carboxyl-2,6-dinitrophenylazohydroxynaphthalenes; Comet assay; DNA damage; Genotoxicity; Human ...	4 [(2 hydroxy 7 (3 oxobutyl)naphthalen 1 yl)diazenyl] 3,5 dinitrobenzoic acid; 4 [(2 hydroxynapht...	None	View
Scopus	2-s2.0-84867237053	The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation ...	Tukulula M., Little S., Gut J., Rosenthal P.J., Wan B., Franzblau S.G., Chibale K.	2012	European Journal of Medicinal Chemistry	57	None	10.1016/j.ejmech.2012.08.047	Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; London School of...	Tukulula, M., Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Li...	A series of new arylamino quinoline derivatives was designed based on the quinine and mefloquine ...	Antimycobacterial; Antiplasmodial; Arylamino quinoline tetrazoles; Physico-chemical properties	4 [(1 tert butyl 1h tetrazol 5 yl)(piperidin 1 yl)methyl] 6 methoxyquinoline; antimalarial agent;...	None	View
Scopus	2-s2.0-71749096148	Evaluation of copper speciation in model solutions of humic acid by mini-columns packed with Chel...	Kiptoo J.K., Ngila J.C., Silavwe N.D.	2009	Journal of Hazardous Materials	172	42403	10.1016/j.jhazmat.2009.07.119	Department of Chemistry, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000-0...	Kiptoo, J.K., Department of Chemistry, Jomo Kenyatta University of Agriculture and Technology, P....	A solid-phase extraction procedure using mini-columns packed with Chelex-100 and two new chelatin...	3-Ferrocenyl-3-hydroxydithioacrylic acid; Chelating agent; Chelex-100; Labile metal fraction; N,N...	3-Ferrocenyl-3-hydroxydithioacrylic acid; Chelating agent; Chelex-100; Ferrocenyl; Labile metals;...	None	View
Scopus	2-s2.0-84940577071	Evaluation of residual stress in stainless steel 316L and Ti6Al4V samples produced by selective l...	Yadroitsev I., Yadroitsava I.	2015	Virtual and Physical Prototyping	10	2	10.1080/17452759.2015.1026045	Department of Mechanical and Mechatronic Engineering, Central University of Technology, Free Stat...	Yadroitsev, I., Department of Mechanical and Mechatronic Engineering, Central University of Techn...	Selective laser melting (SLM) has great potential in additive manufacturing because it enables th...	numerical simulation; residual stress; selective laser melting; stainless steel; titanium alloy	3D printers; Alloy steel; Computer simulation; Melting; Numerical models; Residual stresses; Tita...	None	View
Scopus	2-s2.0-84861540570	Novel size and shape measurements applied to jig plant performance analysis	Voigt A.E., Twalat C.	2012	Journal of the Southern African Institute of Mining and Metallurgy	112	3	None	DebTech, De Beers Group Services (Pty) Ltd., South Africa; Kumba Iron Ore Ltd., South Africa	Voigt, A.E., DebTech, De Beers Group Services (Pty) Ltd., South Africa; Twalat, C., Kumba Iron Or...	Iron ore samples representing the input and output of several jigging experiments were analysed t...	Density; Jig; MDS; Shape; Size	3-dimensional representation; Individual particles; Input and outputs; MDS; Multi-views; Particle...	None	View
Scopus	2-s2.0-33847633972	The impact of ecological variability on the reproductive endocrinology of wild female African ele...	Wittemyer G., Ganswindt A., Hodges K.	2007	Hormones and Behavior	51	3	10.1016/j.yhbeh.2006.12.013	Save the Elephants, P.O. Box 54667, Nairobi, Kenya; Department of Environmental Science, Policy a...	Wittemyer, G., Save the Elephants, P.O. Box 54667, Nairobi, Kenya, Department of Environmental Sc...	Non-invasive endocrine methods enable investigation of the relationship between ecological variat...	African elephant; Demography; Ecology; Feces; Hormone; NDVI; Non-invasive; Population management;...	3beta hydroxy 5alpha pregnan 20 one; animal experiment; article; behavior; birth; controlled stud...	None	View

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