Article Detail
Source | Electronic ID | Title | Authors | Publication Year | Source Title | Volume | Issue | DOI | Affiliations | Authors with Affiliations | Abstract | Author Keywords | Index Keywords▲ | Funding Details | |
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Scopus | 2-s2.0-77955643799 | The impact of the pandemic influenza a(H1N1) 2009 virus on seasonal influenza a viruses in the so... | Blyth C.C., Kelso A., McPhie K.A., Ratnamohan V.M., Catton M., Druce J.D., Smith D.W., Williams S... | 2010 | Eurosurveillance | 15 | 31 | None | Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathol... | Blyth, C.C., Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Cl... | Data collected over winter 2009 by five World Health Organisation National Influenza Centres in t... | None | 2009 H1N1 influenza; article; disease course; disease surveillance; human; infection prevention; ... | None | |
Scopus | 2-s2.0-25444448818 | Impact and mechanisms of action of neurotensin on cardiac contractility in the rat left ventricle | Osadchii O., Norton G., Deftereos D., Badenhorst D., Woodiwiss A. | 2005 | European Journal of Pharmacology | 520 | 42372 | 10.1016/j.ejphar.2005.07.014 | Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, University of th... | Osadchii, O., Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Un... | Using immunoassay measurements, neurotensin was identified in rat ventricular tissue and in coron... | Inotropic effect; Neurotensin; Ventricular contractility | 2 [[1 (7 chloro 4 quinolinyl) 5 (2,6 dimethoxyphenyl) 3 pyrazolyl]carbonylamino] 2 adamantanecarb... | None | |
Scopus | 2-s2.0-33751172520 | Impact of chronic β-adrenoceptor activation on neurotensin-induced myocardial effects in rats | Osadchii O., Norton G., Deftereos D., Muller D., Woodiwiss A. | 2006 | European Journal of Pharmacology | 553 | 42372 | 10.1016/j.ejphar.2006.09.037 | Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, University of th... | Osadchii, O., Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Un... | In heart failure chronic sympathetic activation results in contractile dysfunction in part throug... | Cardiac hypertrophy; Myocardial norepinephrine; Neurotensin; Ventricular contractility | 2 [[1 (7 chloro 4 quinolinyl) 5 (2,6 dimethoxyphenyl) 3 pyrazolyl]carbonylamino] 2 adamantanecarb... | None | |
Scopus | 2-s2.0-79955599161 | Facile transformation of Biginelli pyrimidin-2(1H)-ones to pyrimidines. In vitro evaluation as in... | Singh K., Singh K., Wan B., Franzblau S., Chibale K., Balzarini J. | 2011 | European Journal of Medicinal Chemistry | 46 | 6 | 10.1016/j.ejmech.2011.03.010 | Organic Synthesis Laboratory, Department of Applied Chemical Sciences and Technology, Guru Nanak ... | Singh, K., Organic Synthesis Laboratory, Department of Applied Chemical Sciences and Technology, ... | A series of pyrimidine derivatives bearing amine substituents at C-2 position were obtained from ... | Biginelli compounds; Cytostatic activity; Inhibitors; MABA; Pyrimidines; Tuberculosis | 2 (2 hydroxyphenylamino) 4 methyl 6 phenylpyrimidine 5 carboxylic acid ethyl ester; 2 (3 aminophe... | None | |
Scopus | 2-s2.0-84924292420 | Design, synthesis and evaluation of small molecule imidazo[2,1-b][1,3,4]thiadiazoles as inhibitor... | Patel H.M., Sing B., Bhardwaj V., Palkar M., Shaikh M.S., Rane R., Alwan W.S., Gadad A.K., Noolvi... | 2015 | European Journal of Medicinal Chemistry | 93 | None | 10.1016/j.ejmech.2014.09.002 | Department of Pharmaceutical Chemistry, College of Health Sciences, University of KwaZulu-Natal (... | Patel, H.M., Department of Pharmaceutical Chemistry, College of Health Sciences, University of Kw... | A new series of imidazo[2,1-b][1,3,4]thiadiazoles 5(a-g), 6(a-g), 9(a-i) and 12(a-h) were synthes... | ALK5; Lipinski's rule; Synthesis imidazo [2,1-b][1,3,4]thiadiazole; XP docking | 2 (2 m tolylimidazo[2,1 b][1,3,4]thiadiazol 6 yl)phenol; 2 (2,4 dichlorophenyl) 6 phenylimidazo[2... | National Research Foundation; National Research Foundation | |
Scopus | 2-s2.0-84860390424 | Synthesis, evaluation and application of polycyclic fluorescent analogues as N-methyl-d-aspartate... | Joubert J., Dyk S.V., Green I.R., Malan S.F. | 2011 | European Journal of Medicinal Chemistry | 46 | 10 | 10.1016/j.ejmech.2011.08.008 | Pharmaceutical Chemistry, North-West University, Private Bag 6001, Potchefstroom 2520, South Afri... | Joubert, J., Pharmaceutical Chemistry, North-West University, Private Bag 6001, Potchefstroom 252... | A series of polycyclic fluorescent ligands were synthesised and evaluated in murine striatal syna... | Amantadine; Calcium channels; Fluorescent ligands; NMDAR; Polycyclic | 2 [3 (1 adamantylamino)propyl]isoindole 1 carbonitrile; 3 (1 adamantylamino)propionitrile; 3 [4 a... | None | |
Scopus | 2-s2.0-32244447844 | Evaluation of human liver slices and reporter gene assays as systems for predicting the cytochrom... | Persson K.P., Ekehed S., Otter C., Lutz E.S.M., McPheat J., Masimirembwa C.M., Andersson T.B. | 2006 | Pharmaceutical Research | 23 | 1 | 10.1007/s11095-005-8812-5 | DMPK and Bioanalytical Chemistry, AstraZeneca R and D Mölndal, 431 83 Mölndal, Sweden; Division o... | Persson, K.P., DMPK and Bioanalytical Chemistry, AstraZeneca R and D Mölndal, 431 83 Mölndal, Swe... | Purpose. The aim of the study was to investigate the feasibility of predicting human in vivo cyto... | AhR; CYP induction; Human liver slices; In vitro-in vivo correlation; PXR; Reporter gene assay | 2,3,7,8 tetrachlorodibenzo para dioxin; aromatic hydrocarbon receptor; betamethasone; carbamazepi... | None | |
Scopus | 2-s2.0-80051578942 | Evaluation of four Cameroonian medicinal plants for anticancer, antigonorrheal and antireverse tr... | Mbaveng A.T., Kuete V., Mapunya B.M., Beng V.P., Nkengfack A.E., Meyer J.J.M., Lall N. | 2011 | Environmental Toxicology and Pharmacology | 32 | 2 | 10.1016/j.etap.2011.04.006 | Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon; Department of ... | Mbaveng, A.T., Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon;... | Methanol extracts from the leaves, bark and roots of four Cameroonian medicinal plants, Bersama e... | Anti-gonorrheal; Anti-reverse transcriptase; Anticancer; Medicinal plants | 2,3 bis[2 methoxy 4 nitro 5 sulfophenyl] 2h tetrazolium 5 carboxyanilide inner salt; anilide; ant... | None | |
Scopus | 2-s2.0-35748933532 | Effect of high-pressure homogenization, nonfat milk solids, and milkfat on the technological perf... | Patrignani F., Iucci L., Lanciotti R., Vallicelli M., Mathara J.M., Holzapfel W.H., Guerzoni M.E. | 2007 | Journal of Dairy Science | 90 | 10 | 10.3168/jds.2007-0373 | University of Bologna, Dipartimento di Scienze degli Alimenti, Piazza Goidanich, 60, 47023 Cesena... | Patrignani, F., University of Bologna, Dipartimento di Scienze degli Alimenti, Piazza Goidanich, ... | The aim of this research was the evaluation of the effects of milkfat content, nonfat milk solids... | High-pressure homogenization; Lactobacillus paracasei; Probiotic fermented milk; Response surface... | 2,3 butanedione; acetaldehyde; fat; organic compound; probiotic agent; article; chemistry; dairy ... | None | |
Scopus | 2-s2.0-84906538667 | Design, synthesis and evaluation of Ospemifene analogs as anti-breast cancer agents | Kaur G., Mahajan M.P., Pandey M.K., Singh P., Ramisetti S.R., Sharma A.K. | 2014 | European Journal of Medicinal Chemistry | 86 | None | 10.1016/j.ejmech.2014.08.050 | School of Pharmaceutical Sciences, Apeejay Stya University, Institutional Area, Gurgaon 122001, I... | Kaur, G., School of Pharmaceutical Sciences, Apeejay Stya University, Institutional Area, Gurgaon... | The synthesis of some novel Ospemifene derived analogs and their evaluation as anti-breast cancer... | Anti-breast cancer agents; Docking studies; Ospemifene; SERMs; Tamoxifen | 2 [ 4 ( 4 amino 1,2 diphenylbut 1 enyl)phenoxy]ethanol; 2 [ 4 ( 4 azido 1,2 diphenylbut 1 enyl)ph... | None | |
Scopus | 2-s2.0-84928944900 | Synthesis and evaluation of antimicrobial activity of novel 3-{[1-pyridin-2-yl methylene]amino}-2... | Karthikeyan R., Idhayadhulla A., Manilal A., Merdekios B., Kumar R.S., Nasser A.J.A. | 2015 | Der Pharmacia Lettre | 7 | 4 | None | P.G and Research Department of Chemistry, Jamal Mohamed College, Tiruchirappalli, Tamil Nadu, Ind... | Karthikeyan, R., P.G and Research Department of Chemistry, Jamal Mohamed College, Tiruchirappalli... | New series of 2-thioxo imidazolidin-4-one derivatives were synthesized. The newly synthesized com... | 2-Thioximidazolidin-4-one; Antibacterial activity; Antifungal activity; Mannich base | 2 (4 chlorophenyl)[[[4 oxo 3 (pyridin 2 ylmethylene)amino] 2 thioximidazolidin 1 yl]methyl]hydraz... | None | |
Scopus | 2-s2.0-10444240254 | Exposure to 2,4-decadienal negatively impacts upon marine invertebrate larval fitness | Caldwell G.S., Lewis C., Olive P.J.W., Bentley M.G. | 2005 | Marine Environmental Research | 59 | 5 | 10.1016/j.marenvres.2004.06.005 | Sch. of Mar. Science and Technology, University of Newcastle Upon Tyne, Ridley Bldg., Claremont R... | Caldwell, G.S., Sch. of Mar. Science and Technology, University of Newcastle Upon Tyne, Ridley Bl... | Diatoms liberate volatile, biologically active unsaturated aldehydes following cell damage, which... | Aldehyde; Algal toxins; Decadienal; Developmental abnormality; Fluctuating asymmetry; Larval bioa... | 2,4-decadienal; Cell damage; Embryogenesis; Fertilization; Aldehydes; Cells; Marine biology; Rado... | None | |
Scopus | 2-s2.0-37849019619 | Performance optimization of a membrane assisted passive sampler for monitoring of ionizable organ... | Chimuka L., Nemutandani T., Cukrowska E., Tutu H. | 2008 | Journal of Environmental Monitoring | 10 | 1 | 10.1039/b713072d | School of Chemistry, University of the Witwatersrand, Johannesburg, 2050, South Africa; School of... | Chimuka, L., School of Chemistry, University of the Witwatersrand, Johannesburg, 2050, South Afri... | A thin-walled silicone rubber hollow fibre membrane has been developed as a passive sampler. The ... | None | 2,4 dichlorophenol; 4 chlorophenol; organic compound; river water; aqueous solution; article; ext... | None | |
Scopus | 2-s2.0-56449085002 | Design, synthesis and pharmacological evaluation of novel tetrasubstituted thiophene analogues as... | Molvi K.I., Sudarsanam V., Patel M.M., Haque N. | 2008 | Journal of Enzyme Inhibition and Medicinal Chemistry | 23 | 6 | 10.1080/14756360701608692 | School of Pharmacy, Faculty of Medical Sciences, Jimma University, Jimma, Ethiopia; Department of... | Molvi, K.I., School of Pharmacy, Faculty of Medical Sciences, Jimma University, Jimma, Ethiopia; ... | A new series of tetrasubstituted thiophene analogues (4a-4f, 5a-5f and 8a-8i) were designed incor... | Analgesic activity; Anti-inflammatory activity; Antioxidant activity; COX-inhibitors; Tetrasubsti... | 2 (4 methoxyanilino) 5 (4 nitrobenzoyl) 4 methylthiophene 3 carboxylic acid; 2 (4 methoxylanilino... | None | |
Scopus | 2-s2.0-84930526201 | The impact of vitamin D on the innate immune response to uropathogenic Escherichia coli during pr... | Ramos N.L., Sekikubo M., Kironde F., Mirembe F., Sääf M., Brauner A. | 2015 | Clinical Microbiology and Infection | 21 | 5 | 10.1016/j.cmi.2014.12.010 | Department of Microbiology, Tumour and Cell Biology, Division of Clinical Microbiology, Karolinsk... | Ramos, N.L., Department of Microbiology, Tumour and Cell Biology, Division of Clinical Microbiolo... | Urinary tract infections are highly common during pregnancy, and can cause serious complications ... | 25-hydroxyvitamin D; Escherichia coli; Interleukin-8; LL-37; Pregnancy; Urinary tract infection | 25 hydroxyvitamin D; beta defensin 2; calcitriol; cathelicidin antimicrobial peptide LL 37; CD14 ... | None | |
Scopus | 2-s2.0-84885291083 | Low vitamin D status is associated with reduced muscle mass and impaired physical performance in ... | Tieland M., Brouwer-Brolsma E.M., Nienaber-Rousseau C., Van Loon L.J.C., De Groot L.C.P.G.M. | 2013 | European Journal of Clinical Nutrition | 67 | 10 | 10.1038/ejcn.2013.144 | Top Institute Food and Nutrition, Wageningen, Netherlands; Division of Human Nutrition, Wageninge... | Tieland, M., Top Institute Food and Nutrition, Wageningen, Netherlands, Division of Human Nutriti... | Background/Objectives:Serum 25-hydroxyvitamin D (25(OH)D) status has been associated with muscle ... | aging; frailty; muscle function; sarcopenia; vitamin D | 25 hydroxyvitamin D; vitamin D; aged; article; blood sampling; cross-sectional study; disease ass... | None | |
Scopus | 2-s2.0-84923308388 | Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuber... | Naiker S., Connolly C., Wiesner L., Kellerman T., Reddy T., Harries A., McIlleron H., Lienhardt C... | 2014 | BMC Pharmacology and Toxicology | 15 | 1 | 10.1186/2050-6511-15-61 | Medical Research Council, TB Research Unit, Durban, South Africa; Medical Research Council, Biost... | Naiker, S., Medical Research Council, TB Research Unit, Durban, South Africa; Connolly, C., Medic... | Background: Pharmacokinetic interactions between rifampicin and protease inhibitors (PIs) complic... | Clinical trial; DDI; HIV; Lopinavir; Neutropenia; Pharmacokinetics; Randomized; Rifabutin; Tuberc... | 25 o desacetylrifabutin; aminotransferase; amylase; ethambutol; isoniazid; lamivudine; lopinavir;... | None | |
Scopus | 2-s2.0-77957845582 | Synthesis and anti-prion activity evaluation of aminoquinoline analogues | MacEdo B., Kaschula C.H., Hunter R., Chaves J.A.P., Van Der Merwe J.D., Silva J.L., Egan T.J., Co... | 2010 | European Journal of Medicinal Chemistry | 45 | 11 | 10.1016/j.ejmech.2010.07.054 | Faculdade de Farmácia, Universidade Federal Do Rio de Janeiro, Av Carlos Chagas Filho, Rio de Jan... | MacEdo, B., Faculdade de Farmácia, Universidade Federal Do Rio de Janeiro, Av Carlos Chagas Filho... | Transmissible spongiform encephalopathies form a group of neurodegenerative diseases that affect ... | Aggregation; Antimalarials; Inhibitor; Neurodegeneration; Prion; Quinoline | 2 (7 chloro 4 quinolinyl) aminoethanol; 4 (cyclopentylamino) 7 chloro quinoline; 4 amino 7 chloro... | None | |
Scopus | 2-s2.0-70349774229 | Pentacyclo-undecane derived cyclic tetra-amines: Synthesis and evaluation as potent anti-tubercul... | Onajole O.K., Govender K., Govender P., van Helden P.D., Kruger H.G., Maguire G.E.M., Muthusamy K... | 2009 | European Journal of Medicinal Chemistry | 44 | 11 | 10.1016/j.ejmech.2009.07.015 | School of Chemistry, University of KwaZulu-Natal, Durban, South Africa; Department of Medical Mic... | Onajole, O.K., School of Chemistry, University of KwaZulu-Natal, Durban, South Africa; Govender, ... | As part of an ongoing effort to develop highly potent anti-tuberculosis agents, fourteen pentacyc... | Isoprenyl; Pentacycloundecane; SQ109; XDR-tuberculosis (TB) | 2 (aminomethyl)pyridine pentacyclo undecane; 5 nitrofuran 2 carbonyl homopiperazine pentacyclo un... | None | |
Scopus | 2-s2.0-84879869114 | β-lactam-synthon-interceded synthesis of isatin-imidazolidine-2-thione conjugates with structural... | Nisha, Singh P., Hendricks D., Bisetty K., Kumar V. | 2013 | Synlett | 24 | 14 | 10.1055/s-0033-1339315 | Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, India; Department of Chemist... | Nisha, Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, India; Singh, P., Dep... | β-Lactam-synthon-interceded synthesis of isatin-imidazolidine-2-thione conjugates was carried out... | β-lactam synthon; cytotoxicity; imidazolidine-2-thione; intermolecular amidolysis; molecular dyna... | 2 azetidinone derivative; 3 isothiocyanato 2 azetidinone derivative; beta lactam derivative; beta... | None |