CD4 stabilization tubes provide improved accuracy of absolute CD4 T-cell counts compared to standard K3 EDTA tubes in human immunodeficiency virus immunologic monitoring in resource-poor settings
Clinical and Vaccine Immunology
Clinical Monitoring Research Program, SAIC-Frederick, Inc., NCI-Frederick, Frederick, MD 21702, United States; National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, United States; Rakai Health Sciences Program, Rakai District, Kalisizo, Uganda; Johns Hopkins Medical Institutions, Baltimore, MD, United States; School of Public Health, Makerere University, Kampala, Uganda; SAIC-Frederick, Inc., NIAID/NIH - Uganda, Rakai Health Sciences Program, Rakai District, Kalisizo, Uganda
CD4 stabilization tubes have the ability to ensure internal quality control in the human immunodeficiency virus (HIV) monitoring laboratory by maintaining accurate absolute CD4 T-cell counts for up to 6 days. Here, we assessed this technology for its use in an HIV clinical monitoring laboratory in a resource-poor setting in rural Uganda. Copyright © 2008, American Society for Microbiology. All Rights Reserved.
CD4 antigen; edetic acid; accuracy; article; CD4 lymphocyte count; comparative study; female; human; human cell; Human immunodeficiency virus; Human immunodeficiency virus infected patient; laboratory; major clinical study; male; nonhuman; priority journal; quality control; rural area; technology; tube; Uganda; CD4 lymphocyte count; evaluation; Human immunodeficiency virus infection; immunology; laboratory diagnosis; methodology; CD4 Lymphocyte Count; HIV Infections; Humans; Specimen Handling; Uganda