The impact of stressful life events, symptom status, and adherence concerns on quality of life in people living with HIV
Journal of the Association of Nurses in AIDS Care
MGH Institute of Health Professions, Boston, MA, United States; University of Washington, Seattle, WA, United States; Rutgers University School of Nursing, The State University of New Jersey, Newark, NJ, United States; Texas A and M University-Corpus Christi, Corpus Christi, TX, United States; Harris Health System, Houston, TX, United States; School of Nursing, University of California, San Francisco, CA, United States; University of Puerto Rico Medical Sciences, Campus School of Nursing, San Juan, Puerto Rico; Universidad del Turabo School of Health Sciences, Gurabo, Puerto Rico; School of Nursing, MGH Institute of Health Professions, Boston, MA, United States; University of South Africa, Pretoria, South Africa; Illinois Division, American Cancer Society, Chicago, IL, United States; Middle East Center University of Utah, Salt Lake City, UT, United States; University of San Diego, San Diego, CA, United States
Studies concerning persons living with HIV (PLWH) report that stressful life events (SLEs) contribute to an exacerbation of symptoms and reduced antiretroviral (ARV) adherence and quality of life (QOL). Little is known about whether these findings are site-specific. Our study's aims were to characterize the type and frequency of SLEs for PLWH in Puerto Rico, South Africa, and the United States, and to assess the impact of SLEs by national site, symptoms, and ARV adherence concerns on QOL. The sample consisted of 704 participants. The total number of SLEs correlated significantly with the total number of symptoms, adherence concerns, and QOL (p ≤ .001). Overall, 27.2% of the variance in QOL was explained by the aforementioned variables. Although SLEs were of concern to PLWH, worries about ARV adherence were of even greater concern. Routine assessment of ARV concerns and SLEs can promote ongoing ARV adherence and improved QOL. © 2013 Association of Nurses in AIDS Care.
antiretrovirus agent; adaptive behavior; ADHERENCE; adult; aged; article; cultural factor; ethnology; female; health survey; human; Human immunodeficiency virus; Human immunodeficiency virus infection; life event; male; medication compliance; mental stress; middle aged; psychological aspect; Puerto Rico; quality of life; questionnaire; Sickness Impact Profile; socioeconomics; South Africa; stressful life events; symptoms; United States; young adult; adherence; HIV; quality of life; stressful life events; symptoms; Adaptation, Psychological; Adult; Aged; Anti-Retroviral Agents; Cross-Cultural Comparison; Female; Health Surveys; HIV Infections; Humans; Life Change Events; Male; Medication Adherence; Middle Aged; Puerto Rico; Quality of Life; Questionnaires; Sickness Impact Profile; Socioeconomic Factors; South Africa; Stress, Psychological; United States; Young Adult
P20 NR08359, NIH, National Institutes of Health; P20 NR08342, NIH, National Institutes of Health