Robinson E., Picon D., Sturrock H.J., Sabasio A., Lado M., Kolaczinski J., Brooker S.
Malaria Consortium - Africa Regional Office, Plot 2a, Sturrock Road, Kololo, Kampala, Uganda; Malaria Consortium - Southern Sudan Office, Juba, Sudan; London School of Hygiene and Tropical Medicine, London, United Kingdom; Ministry of Health, Government of Southern Sudan, Juba, Sudan; Kenya Medical Research Institute-Wellcome Trust Research Programme, Nairobi, Kenya
Robinson, E., Malaria Consortium - Africa Regional Office, Plot 2a, Sturrock Road, Kololo, Kampala, Uganda; Picon, D., Malaria Consortium - Southern Sudan Office, Juba, Sudan; Sturrock, H.J., Malaria Consortium - Southern Sudan Office, Juba, Sudan, London School of Hygiene and Tropical Medicine, London, United Kingdom; Sabasio, A., Malaria Consortium - Southern Sudan Office, Juba, Sudan; Lado, M., Ministry of Health, Government of Southern Sudan, Juba, Sudan; Kolaczinski, J., Malaria Consortium - Africa Regional Office, Plot 2a, Sturrock Road, Kololo, Kampala, Uganda, London School of Hygiene and Tropical Medicine, London, United Kingdom; Brooker, S., London School of Hygiene and Tropical Medicine, London, United Kingdom, Kenya Medical Research Institute-Wellcome Trust Research Programme, Nairobi, Kenya
The implementation of programmes to control neglected tropical diseases (NTDs) requires up-to-date information on the prevalence and distribution of each NTD. This study evaluated the performance of reagent strip testing for haematuria to diagnose Schistosoma haematobium infection among school-aged children in the context of a rapid mapping survey in Southern Sudan. The reagent strips were highly sensitive (97.8%) but only moderately specific (58.8%). The proportion of false positive diagnoses was significantly higher among girls than boys, especially among girls aged 5-10 years. These findings suggest that reagent strips alone are not sufficient for rapid mapping surveys. A two-step approach is thus recommended whereby haematuria-positive urine samples are subsequently examined using urine filtration. © 2009 Blackwell Publishing Ltd.
child health; disease control; disease prevalence; health services; health survey; schistosomiasis; urine; article; child; controlled study; diagnostic procedure; female; health survey; hematuria; human; laboratory diagnosis; major clinical study; male; performance; preschool child; Schistosoma hematobium; schistosomiasis; school child; sensitivity and specificity; Sudan; test strip; urinalysis; Adolescent; Age Factors; Child; Child, Preschool; Community Health Services; False Positive Reactions; Female; Hematuria; Humans; Male; Parasite Egg Count; Population Surveillance; Prevalence; Reagent Strips; Schistosomiasis haematobia; Sensitivity and Specificity; Sudan; Africa; East Africa; Sub-Saharan Africa; Sudan; Schistosoma haematobium