Brent A.J., Mugo D., Musyimi R., Mutiso A., Morpeth S., Levin M., Scott J.A.G.
KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108, Kilifi, Kenya; Wellcome Trust Centre for Clinical Tropical Medicine, Imperial College London, London, United Kingdom; Department of Pediatrics, Imperial College London, London, United Kingdom; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
Brent, A.J., KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108, Kilifi, Kenya, Wellcome Trust Centre for Clinical Tropical Medicine, Imperial College London, London, United Kingdom; Mugo, D., KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108, Kilifi, Kenya; Musyimi, R., KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108, Kilifi, Kenya; Mutiso, A., KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108, Kilifi, Kenya; Morpeth, S., KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108, Kilifi, Kenya, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom; Levin, M., Department of Pediatrics, Imperial College London, London, United Kingdom; Scott, J.A.G., KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108, Kilifi, Kenya, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
Rapid MPT64-based immunochromatographic tests (MPT64 ICTs) have been developed to detect Mycobacterium tuberculosis complex (MTBC) in culture. We demonstrated the noninferiority of one commercial MTP64 ICT, the MGIT TBc identification (TBcID) test, to GenoType line probe assays for MTBC identification in positive MGIT cultures. Meta-analysis of MPT64 ICT performance for identification of MTBC in liquid culture confirmed similar very high sensitivities and specificities for all three commercial MPT64 assays for which sufficient data were available. Copyright © 2011, American Society for Microbiology. All Rights Reserved.