Clinical evaluation of the OneStep Gonorrhea RapiCard InstaTest for detection of Neisseria gonorrhoeae in symptomatic patients from KwaZulu-Natal, South Africa
Journal of Clinical Microbiology
HIV Prevention Research Unit, Medical Research Council, Westville, Durban, South Africa; Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom; Infectious Diseases, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa; Infection Prevention and Control, KwaZulu-Natal Department of Health, Durban, South Africa; Biostatistics Unit, Medical Research Council, Durban, South Africa
We evaluated a point-of-care test for the detection of Neisseria gonorrhoeae in patients attending a public health clinic in KwaZulu-Natal, South Africa. The test showed a low sensitivity against PCR and culture (<40%); however, a higher specificity was observed (>95%). This test is unsuitable as a screening tool for gonorrhea. Copyright © 2015, American Society for Microbiology. All Rights Reserved.
bacterial antigen; Article; bacterium culture; bacterium detection; bioassay; female; gonorrhea; human; human tissue; intermethod comparison; major clinical study; male; Neisseria gonorrhoeae; nonhuman; OneStep Gonorrhea RapiCard InstaTest; point of care testing; polymerase chain reaction; priority journal; sensitivity and specificity; South Africa; strand displacement amplification assay; Neisseria gonorrhoeae