HIV Prevention Unit, Medical Research Council, Durban, South Africa
Wand, H.; Ramjee, G., HIV Prevention Unit, Medical Research Council, Durban, South Africa
The objective of this study was to estimate the joint impact of demographic and sexual risk behaviors on HIV acquisition. A total of 2,523 HIV seronegative women were recruited through three community based studies in Durban, South Africa. Point and interval estimates of partial population attributable risk (PAR) were used to quantify the proportion of HIV seroconversions which can be prevented if a combination of risk factors is eliminated from a target population. More than 80% of the observed HIV acquisitions were attributed to five risk factors: lack of cohabitation, frequency of sex, sexually transmitted infections (STIs), incidence of pregnancy and not being employed/no income. Structural factors such as minimizing migratory patterns by ensuring cohabitation of partners, access to treatment of STIs, income generation and safe sex negotiation skills are likely to play an important role in future prevention strategies. © 2010 Springer Science+Business Media, LLC.
adult; age; article; female; follow up; health care policy; high risk behavior; human; Human immunodeficiency virus infection; incidence; pregnancy; questionnaire; risk factor; sexual behavior; sexuality; sexually transmitted disease; socioeconomics; South Africa; Adult; Age Factors; Female; Follow-Up Studies; Health Policy; HIV Infections; HIV Seropositivity; Humans; Incidence; Pregnancy; Questionnaires; Risk Factors; Risk-Taking; Sexual Behavior; Sexual Partners; Sexually Transmitted Diseases; Socioeconomic Factors; South Africa; Young Adult