Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johannesburg, South Africa; Pharmacology Division, Department of Pharmacy and Pharmacology, University of the Witwatersrand, 7 York Road, Parktown 2193, South Africa; Department of Biochemistry, University of Johannesburg, PO Box 524, Auckland Park, 2006, South Africa; Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, PO Wits 2050, Johannesburg, South Africa; Pharmaceutical Chemistry, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa
Gravestock, D., Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johannesburg, South Africa; Rousseau, A.L., Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johannesburg, South Africa, Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, PO Wits 2050, Johannesburg, South Africa; Lourens, A.C.U., Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johannesburg, South Africa, Pharmaceutical Chemistry, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa; Moleele, S.S., Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johannesburg, South Africa; Van Zyl, R.L., Pharmacology Division, Department of Pharmacy and Pharmacology, University of the Witwatersrand, 7 York Road, Parktown 2193, South Africa; Steenkamp, P.A., Discovery Chemistry, CSIR Biosciences, Private Bag X2, Modderfontein 1645, Johannesburg, South Africa, Department of Biochemistry, University of Johannesburg, PO Box 524, Auckland Park, 2006, South Africa
2 phenyl n 6 (3 (2,4,6 trichlorophenoxy)propyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; 4,6 diamino 1,2 dihydro 2,2 dimethyl 1 [3 (2,4,5 trichlorophenoxy)propoxy] 1,3,5 triazine; antimalarial agent; cycloguanil; diamine derivative; n 4 (3 (4 chlorophenoxy)propyl) 1,3,5 triazaspiro[5.5]undeca 1,3 diene 2,4 diamine; n 4 benzyl 1,3,5 triazaspiro[5.5]undeca 1,3 diene 2,4 diamine; n 6 (3 (2 fluorophenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (2,4 dichlorophenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (3,4 dichlorophenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 (2 chlorophenyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 (4 (dimethylaminol)phenyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 (4 (trifluoromethyl)phenyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 (4 fluorophenyl)1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 (4 methoxyphenyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 (4 nitrophenyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 (furan 2 yl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 cyclohexyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenoxy)propyl) 2,2 dimethyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenylthio)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 chlorophenylthio)propyl) 2,2 dimethyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 methoxyphenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3 (4 nitrrophenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3,4 dichlorophenethyl) 2 (4 fluorophenyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (3,4 dichlorophenethyl) 2 (4 nitrophenyl) 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (4 (4 chlorophenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (4 chlorophenethyl) 2,2 dimethyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 (5 (4 chlorophenoxy)propyl) 2 phenyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; n 6 benzyl 2,2 dimethyl 1,2 dihydro 1,3,5 triazine 4,6 diamine; unclassified drug; antimalarial activity; article; binding site; drug synthesis; erythrocyte; hemolysis; IC 50; nonhuman; Plasmodium falciparum; substitution reaction; Antimalarials; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Triazines