Nanyonjo A., Ssekitooleko J., Counihan H., Makumbi F., Tomson G., Källander K.
Department of Public Health Sciences, Karolinska Institutet, Tomtebodavägen 18 A, Floor 4Stockholm, Sweden; Malaria Consortium Uganda Office, Plot 25, Upper East Naguru, P.O. Box 8045Kampala, Uganda; Malaria Consortium, Development House, 56-64 Leonard StreetLondon, United Kingdom; Department of Epidemiology and Biostatistics, Makerere University, New Mulago Hospital Complex, P.O. Box 7062Kampala, Uganda; Medical Management Centre (MMC), Karolinska InstitutetStockholm, Sweden
Nanyonjo, A., Department of Public Health Sciences, Karolinska Institutet, Tomtebodavägen 18 A, Floor 4Stockholm, Sweden, Malaria Consortium Uganda Office, Plot 25, Upper East Naguru, P.O. Box 8045Kampala, Uganda; Ssekitooleko, J., Malaria Consortium Uganda Office, Plot 25, Upper East Naguru, P.O. Box 8045Kampala, Uganda; Counihan, H., Malaria Consortium, Development House, 56-64 Leonard StreetLondon, United Kingdom; Makumbi, F., Department of Epidemiology and Biostatistics, Makerere University, New Mulago Hospital Complex, P.O. Box 7062Kampala, Uganda; Tomson, G., Department of Public Health Sciences, Karolinska Institutet, Tomtebodavägen 18 A, Floor 4Stockholm, Sweden, Medical Management Centre (MMC), Karolinska InstitutetStockholm, Sweden; Källander, K., Department of Public Health Sciences, Karolinska Institutet, Tomtebodavägen 18 A, Floor 4Stockholm, Sweden, Malaria Consortium, Development House, 56-64 Leonard StreetLondon, United Kingdom, Department of Epidemiology and Biostatistics, Makerere University, New Mulago Hospital Complex, P.O. Box 7062Kampala, Uganda
Introduction: Pneumonia and diarrhoea disproportionately affect children in resource-poor settings. Integrated community case management (iCCM) involves community health workers treating diarrhoea, pneumonia and malaria. Studies on impact of iCCM on appropriate treatment and its effects on equity in access to the same are limited. The objective of this study was to measure the impact of integrated community case management (iCCM) as the first point of care on uptake of appropriate treatment for children with a classification of pneumonia (cough and fast breathing) and/or diarrhoea and to measure the magnitude and distribution of socioeconomic status related inequality in use of iCCM. Methods: Following introduction of iCCM, data from cross-sectional household surveys were examined for socioeconomic inequalities in uptake of treatment and use of iCCM among children with a classification of pneumonia or diarrhoea using the Erreygers' corrected concentration index (CCI). Propensity score matching methods were used to estimate the average treatment effects on the treated (ATT) for children treated under the iCCM programme with recommended antibiotics for pneumonia, and ORS plus or minus zinc for diarrhoea. Findings: Overall, more children treated under iCCM received appropriate antibiotics for pneumonia (ATT = 34.7 %, p < 0.001) and ORS for diarrhoea (ATT = 41.2 %, p < 0.001) compared to children not attending iCCM. No such increase was observed for children receiving ORS-zinc combination (ATT = -0.145, p < 0.05). There were no obvious inequalities in the uptake of appropriate treatment for pneumonia among the poorest and least poor (CCI = -0.070; SE = 0.083). Receiving ORS for diarrhoea was more prevalent among the least poor groups (CCI = 0.199; SE = 0.118). The use of iCCM for pneumonia was more prevalent among the poorest groups (CCI = -0.099; SE = 0.073). The use of iCCM for diarrhoea was not significantly different among the poorest and least poor (CCI = -0.073; SE = 0.085). Conclusion: iCCM is a potentially equitable strategy that significantly increased the uptake of appropriate antibiotic treatment for pneumonia and ORS for diarrhoea, but not the uptake of zinc for diarrhoea. For maximum impact, interventions increasing zinc uptake should be considered when scaling up iCCM programmes. © 2015 Nanyonjo et al.