Department of Psychiatry, University of Ibadan, Ibadan, Nigeria; Department of Medicine, University of Ibadan, Ibadan, Nigeria
Gureje, O., Department of Psychiatry, University of Ibadan, Ibadan, Nigeria, Department of Medicine, University of Ibadan, Ibadan, Nigeria; Ogunniyi, A., Department of Psychiatry, University of Ibadan, Ibadan, Nigeria, Department of Medicine, University of Ibadan, Ibadan, Nigeria; Kola, L., Department of Psychiatry, University of Ibadan, Ibadan, Nigeria, Department of Medicine, University of Ibadan, Ibadan, Nigeria
Objective: This study aimed to determine the profile of dementia in a sub-Saharan Africa country and assess its effects on role functioning and quality of life. Methods: Using a multistage, stratified, clustered sampling of households in the Yoruba-speaking areas of Nigeria, representing 22% of the national population, 2152 persons aged 65 years and above were studied. Probable dementia was evaluated using a validated cognitive test - the 10-Word Delay Recall Test. Activities of daily living (ADL), instrumental ADL, and quality of life were also assessed. Results: The prevalence of probable dementia in this sample was 10.1% (95% confidence interval, 8.6-11.8). Female sex and increasing age were risk factors. Also, lifetime history of alcohol use doubles the risk. Affected persons had relatively preserved functioning and quality of life. Conclusion: The findings suggest that the diagnosis of dementia may be downwardly biased in this culture due to relatively preserved levels of social and functional roles. © 2006 Elsevier Inc. All rights reserved.
Africa; age distribution; aged; aging; anamnesis; article; controlled study; dementia; evaluation; female; human; major clinical study; male; Nigeria; quality of life; risk factor; sex ratio; validation process; Africa South of the Sahara; Aged; Aging; Cognition Disorders; Dementia; Female; Humans; Male; Neuropsychological Tests; Prevalence; Quality of Life; Severity of Illness Index; Sickness Impact Profile