Management of sickle cell anemia in Nigeria with medicinal plants: Cationic evaluation of extracts and possible effects on the efficacy
Journal of Biological Sciences
Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria; Department of Pharmacognosy, Faculty of Pharmacy, University of Lagos, PMB 12003, Suru Lere, Lagos, Nigeria
Eleven aqueous plant extracts from 8 traditionally used Nigerian medicinal plants Adasonia digitata L. (Bombacaceae), Bryophyllum pinnatum Lam. (Crassulaceae), Cajanus cajan (L.) Mill sp. (Fabaceae), Carica papaya L. (Caricaceae), Cissus populnea Guill and Perr (Vitaceae) Parquetina nigrescens (Afzel.) Bullock (Periplocaceae), (Terminalia catappa L.) (Combretaceae) and Zanthoxylum xanthoxyloides (Lam.) Waterman (Rutaceae) were evaluated for their cationic constituents as a measure of their efficacy in sickle cell anemia disorder. Extracts were subjected to dry ash digestion and the resultant supernatants were used for macro- and micronutrients determination using the emission flame photometer and the absorption spectrophotometer. K+, Na+, Fe2+ and Zn2+ were relatively higher than Ca2+ and Mg2+ in the tested extracts. The presence of these cations, K+, Na+, Ca2+ and Mg2+ implicated in the process of sickling and involved in electrolytes movement in the physiological system of the body may be an important parameter in sickle cell anemia management. © 2006 Asian Network for Scientific Information.
Adasonia digitata extract; bryophyllum pinnatum extract; Cajanus cajan extract; calcium ion; Carica papaya extract; cation; Cissus populnea extract; herbaceous agent; iron; magnesium ion; Parquetina nigrescens extract; plant extract; potassium ion; sodium ion; Terminalia catappa extract; trace element; unclassified drug; water; zanthoxylum xanthoxyloides extract; zinc ion; absorption spectrophotometry; aqueous solution; article; controlled study; drug efficacy; electrolyte transport; extraction; flame photometry; macronutrient; medicinal plant; Nigeria; sickle cell anemia; supernatant; Cajanus cajan; Carica papaya; Caricaceae; Cissus populnea; Combretaceae; Crassulaceae; Fabaceae; Kalanchoe pinnata; Malvaceae; Parquetina nigrescens; Periplocoideae; Rutaceae; Terminalia catappa; Vitaceae; Zanthoxylum xanthoxyloides