Markotter W., York D., Sabeta C.T., Shumba W., Zulu G., Roux K.L.E., Nel L.H.
Department of Microbiology and Plant Pathology, University of Pretoria, Pretoria, 0002, South Africa; Molecular Diagnostic Services, Private Bag X20, Westville, Durban, Kwazulu Natal, 3630, South Africa; OIE Rabies Reference Laboratory, Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort, 0110, South Africa; Allerton Veterinary Laboratory, Private Bag X2, Cascades, Pietermaritzburg, 3202, South Africa
Markotter, W., Department of Microbiology and Plant Pathology, University of Pretoria, Pretoria, 0002, South Africa; York, D., Molecular Diagnostic Services, Private Bag X20, Westville, Durban, Kwazulu Natal, 3630, South Africa; Sabeta, C.T., OIE Rabies Reference Laboratory, Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort, 0110, South Africa; Shumba, W., OIE Rabies Reference Laboratory, Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort, 0110, South Africa; Zulu, G., OIE Rabies Reference Laboratory, Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort, 0110, South Africa; Roux, K.L.E., Allerton Veterinary Laboratory, Private Bag X2, Cascades, Pietermaritzburg, 3202, South Africa; Nel, L.H., Department of Microbiology and Plant Pathology, University of Pretoria, Pretoria, 0002, South Africa
A rapid immunodiagnostic test kit was evaluated against a selection of isolates of lyssavirus genotypes occurring in Africa. The test was carried out in parallel comparison with the fluorescent antibody test (FAT) and isolates representing previously established phylogenetic groups from each genotype were included. The specificity of the rapid immunodiagnostic test compared favourably with the FAT and was found to detect all representatives of genotypes 1, 2, 3 and 4 in brain samples of either field cases or suckling mouse brain inoculates.