Department of Maxillofacial and Oral Surgery, University of Pretoria, P.O. Box 1266, Pretoria 0001, South Africa; Maxillo-Facial and Oral Surgery, University of Pretoria (1 Military Hospital Division), South Africa
Syebele, K., Department of Maxillofacial and Oral Surgery, University of Pretoria, P.O. Box 1266, Pretoria 0001, South Africa; Munzhelele, T.I., Maxillo-Facial and Oral Surgery, University of Pretoria (1 Military Hospital Division), South Africa
Objectives: The study's aim was to assess the potential therapeutic effect of highly active antiretroviral therapy (HAART) on ranulas in human immunodeficiency virus (HIV)-positive patients. Study Design: The study includes a retrospective observation of 3 patients who were initially part of a prospective study on the comparative effect of HAART on ranulas in 14 HIV-positive patients. These patients were clinically monitored while pursuing the medical treatment with HAART. Neither a fine needle aspiration nor a surgical procedure was performed. Clinical photographs were used for monitoring of any reduction in the ranula size. The effect of HAART on ranula was assessed at 3, 6 and 12 month. Results: A complete resolution of the ranula lesion was noticed in the 3 HIV-positive selected patients. These results were observed between 6 and 12 months period. Conclusion: This study suggests that HAART might present a potential therapeutic effect on ranula in HIV-positive patients. © 2013 Elsevier Inc. All rights reserved.
adult; article; case report; child; female; highly active antiretroviral therapy; human; Human immunodeficiency virus infection; mucocele; preschool child; retrospective study; salivary gland disease; Adult; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Female; HIV Seropositivity; Humans; Ranula; Retrospective Studies; Salivary Gland Diseases