Bacteriology Section, ARC-Onderstepoort Veterinary Institute, Private Bag x05, Onderstepoort, 0110, South Africa; UTAD (Universidade de Tras-os-Montes e Alto Douro) and ACD (Associacao Ciencia para o Desenvolviment, Portugal
Michel, A.L., Bacteriology Section, ARC-Onderstepoort Veterinary Institute, Private Bag x05, Onderstepoort, 0110, South Africa; Simões, M., UTAD (Universidade de Tras-os-Montes e Alto Douro) and ACD (Associacao Ciencia para o Desenvolviment, Portugal
Panels of sera from African buffalo with confirmed bovine tuberculosis and from known uninfected controls were used to evaluate the performance of two commercial rapid chromatographic immunoassays (A and B) for the detection of antibodies to Mycobacterium bovis. The sensitivity was 33% and 23%, respectively, while the specificity was determined at 90% and 94%, respectively. Overall the performance of both diagnostic tests under field conditions was not found sufficiently high to support their use in bovine tuberculosis management and control strategies in South African game reserves. © 2008 Elsevier B.V. All rights reserved.
animal experiment; animal model; article; buffalo; controlled study; diagnostic test; immunoassay; Mycobacterium bovis; nonhuman; sensitivity and specificity; serodiagnosis; Syncerus caffer; tuberculosis; Animals; Animals, Wild; Antibodies, Bacterial; Buffaloes; Case-Control Studies; Immunoassay; Mycobacterium bovis; Sensitivity and Specificity; South Africa; Tuberculosis; Bovinae; Mycobacterium bovis; Syncerus caffer