Olowosusi O.Z., Asoegwu C.N., Olagunju A.T., Nwawolo C.C.
Department of Ear, Nose and Throat Surgery, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria; Department of Psychiatry, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria
Olowosusi, O.Z., Department of Ear, Nose and Throat Surgery, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria; Asoegwu, C.N., Department of Ear, Nose and Throat Surgery, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria; Olagunju, A.T., Department of Psychiatry, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria; Nwawolo, C.C., Department of Ear, Nose and Throat Surgery, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria
Quality of Life (QoL) studies are increasingly being used as the primary outcome measure in chronic rhinosinusitis (CRS) globally. However, little is known about QoL and the interplay of identifiable factors on QoL in CRS in sub-Saharan Africa. This study investigated the correlation between disease severity and QoL in chronic rhinosinusitis patients. A total of 147 adults with subjective severity rating of CRS were studied. Participants were assessed using designed questionnaire, Individual Rhinosinusitis Symptom Severity Score Assessment (IRSSSA) and Rhinosinusitis Disability Index (RSDI) questionnaires to elicit socio-demographic/clinical profile, CRS symptom severity and QoL, respectively. The mean age of the participants was 36.86 ± 11.91 years. The mean severity score of all 147 CRS cases was 3.8 ± 1.13. The majority of participants (N = 80; 54.4 %) had moderate disease. The RSDI mean scores for the participants for overall HRQoL were 40.6 ± 19.8. (Median = 40; Range = 77), for physical domain 15.2 ± 7.7, functional domain 12.1 ± 6.4 and emotional domain 13.2 ± 8.2. The trend of association between the disease severity scores and the overall HRQoL on Pearson linear correlation indicates a positive linear association of worsening overall HRQoL with increasing disease severity (R = 0.83; P < 0.0001). The severity of CRS impacted negatively on the HRQoL. All domains were significantly affected by the disease severity particularly the physical domain. Patients adjudged severity of their disease and its’ impact on their quality of life should be considered in the determination of the line of their management which could include psychosocial intervention. © 2014, Springer-Verlag Berlin Heidelberg.
adult; aged; Article; chronic rhinosinusitis; correlational study; cross-sectional study; disease severity; disease severity assessment; emotion; female; functional status; human; Individual Rhinosinusitis Symptom Severity Score Assessment; major clinical study; male; Nigeria; physical activity; priority journal; quality of life; quality of life assessment; Rhinosinusitis Disability Index; adolescent; chronic disease; middle aged; psychology; rhinitis; severity of illness index; sinusitis; young adult; Adolescent; Adult; Aged; Chronic Disease; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Nigeria; Quality of Life; Rhinitis; Severity of Illness Index; Sinusitis; Young Adult