Evaluation of the effect of azo group on the biological activity of 1-(4-Methylphenylazo)-2-naphthol
Department of Chemistry, University of Uyo, P. M. B. 1017, Uyo, Nigeria; Department of Science and Technology, Akwa Ibom State Polytechnic, P.M.B. 200, Ikot Ekpene, Nigeria
Azo-2-naphthol and 2-naphthol were tested against five microorganisms: Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa and Streptococcus faecalis. 2-Naphthol was slightly active while azo-2-naphthol was highly active against all the bacteria species tested. The presence of azo group contributed more than 60% of the antibacterial activities exhibited by azo-2-naphthol on all the bacteria tested.