Kotaiah Y., Hari Krishna N., Naga Raju K., Rao C.V., Jonnalagadda S.B., Maddila S.
Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India; School of Chemistry, University of KwaZulu-Natal, Durban 4000, South Africa
Kotaiah, Y., Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India; Hari Krishna, N., Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India; Naga Raju, K., Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India; Rao, C.V., Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India; Jonnalagadda, S.B., Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India; Maddila, S., School of Chemistry, University of KwaZulu-Natal, Durban 4000, South Africa
In the present study, we have synthesized novel Isopropyl 2-(4-substitutedbenzylidene)-5-methyl-3-oxo-7-phenyl-3,7-dihydro-2H-thiazolo[3, 2-a]-pyrimidine-6-carboxylate derivatives (6a-j). Elemental analysis, IR, 1H NMR and mass spectral data elucidated structure of newly synthesized compounds. The newly synthesized compounds were screened for antiinflammatory and anti microbial studies. Their biological activity data of the 10 compounds indicates that two compounds posses potent anti-inflammatory and five have antimicrobial activities.