Department of ChemicalScience, College of Sciences, Afe Babalola University, P.M.B 5454, Ado-Ekiti, Nigeria; Department ofBiochemistry, Ekiti State University, P.M.B 5363, Ado-Ekiti, Nigeria
Afolabi, O.B., Department of ChemicalScience, College of Sciences, Afe Babalola University, P.M.B 5454, Ado-Ekiti, Nigeria; Oloyede, O.I., Department ofBiochemistry, Ekiti State University, P.M.B 5363, Ado-Ekiti, Nigeria
The effect of water extract of Talinum triangulare was investigated on the activities of enzymes such as aspartate amino transaminase (AST), alanine amino transaminase (ALT) and alkaline phosphatase (ALP), in the serum and tissue homogenates of an adult albino rats along with the serum total protein. The rats were randomly distributed into four treatment groups A-D; with groups B to D administered with 100, 200 and 400 mg/kg body weights orally and the control group A with water orally respectively. The aqueous extract was prepared using the air-dried leaves parts of the plant following a standardized method with the final yield been considered. The serum total protein (g/dl) was significantly different (p<0.05) relatively compared to control group. In the same vein, statistical data of the activities (u/l) of the enzymes was significantly different (P<0.05) in aspartate aminotransaminase (AST) and alanine aminotransaminase (ALT) when compared to control groups but significant different (p>0.05) in alkaline phosphatase (ALP) when compared to the control group. © 2015, SILAE (Italo-Latin American Society of Ethnomedicine). All rights reserved.
alanine aminotransferase; alkaline phosphatase; aspartate aminotransferase; liver protective agent; plant extract; Talinum triangulare extract; unclassified drug; adult; alanine aminotransferase blood level; alkaline phosphatase blood level; animal experiment; animal tissue; Article; aspartate aminotransferase blood level; controlled study; dose response; drug dose comparison; drug effect; drug mechanism; enzyme activity; medicinal plant; nonhuman; plant leaf; protein blood level; rat; Talinum triangulare; tissue homogenate; tissue level