Department of Botany and Microbiology, University of Ibadan, Nigeria; Department of Biological Sciences, Niger Delta University, Wilberforce Island, Nigeria
Jonathan, S.G., Department of Botany and Microbiology, University of Ibadan, Nigeria; Kigigha, L.T., Department of Biological Sciences, Niger Delta University, Wilberforce Island, Nigeria; Ohimain, E., Department of Biological Sciences, Niger Delta University, Wilberforce Island, Nigeria
Studies were carried out to determine antimicrobial potentials of crude and purified methanol extracts of some selected Nigerian mushrooms against some selected pathogenic microorganisms. The best in vitro antibacterial activity (24.0mm) was observed with the purified extract (PRE) of Polyporus giganteus against E. coli. This was followed in order by PRE of Pleurotus florida against K. pneumoniae with 22.0mm (P ≤ 0.05). Among the screened higher fungi, only the extracts of Pleurotus tuber-regium, were able to inhibit the growth of P. aeruginosa. It was also observed that antifungal activities of these mushrooms were generally low. Candida albicans were inhibited by the extracts of P. giganteus and T. robustus only while other fungi produce no zone of inhibition The observed minimum inhibitory concentration (MIC) of M. jodocodo against E. coli was 2.75mg/ml while that of T. robustus against M. bourlardii was 15.75mg/ml. The significance of these observations was discussed. © Ibadan Biomedical Communications Group.
antifungal agent; antiinfective agent; Fomes lignosus extract; Marasmius jodocodo extract; plant extract; Pleurotus florida extract; Pleurotus tuber regium extract; Polyporus giganteus extract; Psathyrella atroumbonata extract; Termitomyces microcarpus extract; Termitomyces robustus extract; unclassified drug; antibacterial activity; antifungal activity; article; bacterial growth; Candida albicans; controlled study; edible mushroom; Escherichia coli; Fomes lignosus; growth inhibition; in vitro study; Klebsiella pneumoniae; Marasmius jodocodo; minimum inhibitory concentration; nonhuman; Pleurotus; Pleurotus florida; Pleurotus tuber regium; Polyporus giganteus; Psathyrella atroumbonata; Pseudomonas aeruginosa; Termitomyces microcarpus; Termitomyces robustus