Phytochemical screening and antibacterial evaluation of the leaves extracts of olea hochstetteri bak. (Oleaceae)
Research Journal of Pharmacology
Department of Animal Health and Production Technology, Adamawa State College of Agriculture, Ganye, Nigeria; Department of Veterinary Physiology, Pharmacology and Biochemistry, University of Maiduguri, Nigeria; Department of Animal Health and Production T
Phytochemical and antibacterial properties of Olea hochstetteri crude aqueous and ethanol leaf extracts were evaluated. The extracts were subjected to qualitative chemical analysis for identification of various classes of active chemical compounds. Disc diffusion method was used to determine the antibacterial properties of the extracts on some gram positive and gram negative bacteria. The extracts showed the presence of carbohydrates, tannins, saponins, glycosides, flavonoids, terpenes and steroids. The extract inhibited the growth of Pseudomonas aeroginosa, Staphylococcus aureus, Salmonella typhi and to some extent Klebsiella pneumonia but had no effect on the growth of Bacillus sp., Shigella sp. and Escherichia coli. The study revealed some antibacterial properties of this extracts that supported the use of the leaves of this plant in folklore medicine. © Medwell Joumals, 2010.
alcohol; antiinfective agent; carbohydrate derivative; flavonoid; glycoside; Olea hochstetteri extract; plant extract; saponin derivative; steroid; tannin derivative; terpene derivative; unclassified drug; antibacterial activity; article; Bacillus; bacterial growth; bacterium culture; chemical analysis; chemical composition; controlled study; disk diffusion; drug determination; drug isolation; Escherichia coli; Gram negative bacterium; Gram positive bacterium; growth inhibition; Klebsiella pneumoniae; minimum inhibitory concentration; nonhuman; Olea hochstetteri; Oleaceae; phytochemistry; plant leaf; Pseudomonas aeruginosa; qualitative analysis; Salmonella typhi; Shigella; Staphylococcus aureus