Gure A., Lara F.J., García-Campaña A.M., Megersa N., Del Olmo-Iruela M.
Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Campus Fuentenueva s/n, Granada, Spain; Department of Chemistry, Addis Ababa University, P. O. Box 1176, Addis Ababa, Ethiopia
Gure, A., Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Campus Fuentenueva s/n, Granada, Spain, Department of Chemistry, Addis Ababa University, P. O. Box 1176, Addis Ababa, Ethiopia; Lara, F.J., Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Campus Fuentenueva s/n, Granada, Spain; García-Campaña, A.M., Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Campus Fuentenueva s/n, Granada, Spain; Megersa, N., Department of Chemistry, Addis Ababa University, P. O. Box 1176, Addis Ababa, Ethiopia; Del Olmo-Iruela, M., Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Campus Fuentenueva s/n, Granada, Spain
A new sample treatment, namely vortex-assisted ionic liquid dispersive liquid-liquid microextraction (VA-IL-DLLME), followed by capillary liquid chromatography has been developed for the determination of four sulfonylurea herbicides (SUHs): flazasulfuron (FS), prosulfuron (PS), primisulfuron-methyl (PSM) and triflusulfuron-methyl (TSM) in wine samples. The ionic liquid (IL) 1-hexyl-3-methylimidazolium hexafluorophosphate ([C6MIM][PF6]) was used as extraction solvent and was dispersed using methanol into the sample solution, assisted by a vortex mixer. Various parameters influencing the extraction efficiency, such as type and amount of IL, type and volume of disperser solvent, sample pH, salting-out effect, vortex and centrifugation time were studied. Under the optimum conditions, the limits of detection and quantification of the proposed method were in the ranges of 3.2-6.6 and 10.8-22.0 μg kg-1, respectively; lower than the maximum residue limits set by the EU for these matrices. The proposed method was successfully applied to different wine samples and satisfactory recoveries were obtained. © 2014 Elsevier Ltd. All rights reserved.
Capillary high-performance liquid chromatography; Capillary liquid chromatography; Dispersive liquid-liquid microextraction; Sulfonylurea herbicides; Vortex-assisted dispersive liquid-liquid microextraction; Wine sample; Ionic liquids; flazasulfuron; herbicide; imidazole derivative; ionic liquid; methanol; primisulfuron methyl; prosulfuron; sulfonylurea derivative; triflusulfuron methyl; unclassified drug; herbicide; ionic liquid; solvent; sulfonylurea derivative; Article; capillary high performance liquid chromatography; centrifugation; high performance liquid chromatography; limit of detection; limit of quantitation; liquid phase microextraction; pH; solvent extraction; vortex assisted ionic liquid dispersive liquid liquid microextraction; wine; analysis; chemistry; high performance liquid chromatography; procedures; wine; Chromatography, High Pressure Liquid; Herbicides; Ionic Liquids; Solvents; Sulfonylurea Compounds; Wine